345295-14-9

Upstream product

• 345295-12-7 (S)-5-acetoxymethyl-3-[2-(dimethylphosphono)-ethenyl]-1-(2-nitro-benzoyl)-2-pyrroline 
• 610-14-0 2-nitrobenzyl chloride 
• 67040-46-4 (5S)-5-[(1-ethoxyethyl)oxymethyl]tetrahydro-1H-2-pyrrolone 
• 345295-10-5 (5S)-5-(1-ethoxy-ethoxymethyl)-1-(2-nitro-benzoyl)-pyrrolidin-2-one 
• 105243-50-3 (5S)-5-(1-ethoxy-ethoxymethyl)-1-(2-nitro-benzoyl)-pyrrolidin-2-ol 
• 135159-24-9 (S)-5-acetoxymethyl-3-formyl-1-(2-nitro-benzoyl)-2-pyrroline 
• 135159-21-6 (S)-5-acetoxymethyl-1-(2-nitro-benzoyl)-2-pyrroline 
• 345295-13-8 (S)-3-[2-(dimethylphosphono)-ethenyl]-5-hydroxymethyl-1-(2-nitro-benzoyl)-2-pyrroline 

Relevant academic research and scientific papers

Synthesis of a new structural analogue of (+)-porothramycin

A new phosphonate analogue of (+)-porothramycin has been synthesized from (S)-pyroglutaminol. Circular dichroism of diastereomeric intermediates 9 has been studied. The cytostatic activity of the new pyrrolo[2,1-c][1,4]benzodiazepine has been evaluated against human KB cells.