3458-19-3Relevant academic research and scientific papers
6-benayl aminopurine synthetic method
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Paragraph 0020; 0021, (2018/07/30)
The invention discloses a 6-benayl aminopurine synthetic method. The method takes hypoxanthine as a raw material, thionyl chloride is taken as a solvent, phosgene or diphosgene or triphosgene is takenas a chloride agent, 4-dimethylaminopyridine or dialkyl aminopyridine is taken as a catalyst for a reaction, after the reaction is completed, 6-chloropurine is obtained, distilled thionyl chloride and phosgene dissolved in thionyl chloride are completely used for a next reaction, and then the obtained 6-chloropurine and benzylamine are subjected to the reaction to synthesize 6-benayl aminopurineunder existence of triethylamine. During a reaction process, the used chloride agent solid triphosgene is completely decomposed to the phosgene dissolved in the solvent under existence of the catalyst4-dimethylaminopyridine, and no solid constituent is residual.
Selective and recyclable rhodium nanocatalysts for the reductive N-alkylation of nitrobenzenes and amines with aldehydes
Huang, Lei,Wang, Zhi,Geng, Longfei,Chen, Rizhi,Xing, Weihong,Wang, Yong,Huang, Jun
, p. 56936 - 56941 (2015/07/15)
Rhodium nanocatalysts were prepared and applied for the reductive N-alkylation of nitrobenzenes and amines to the corresponding secondary amines with aldehydes and ketones. Functional nitrobenzenes, such as nitrobenzenes with F, Cl, Br, CH3O and CH3 were transformed to the corresponding secondary amines in good to excellent yields. Moreover, the Rh@CN catalyzed N-alkylation of a series of primary amines with aldehydes and ketones also gave the corresponding secondary amines in high yields. The Rh@CN is heterogeneous, and can be reusable several times (at least 4 times) for the reductive N-alkylation of nitroarenes.
