34582-07-5Relevant articles and documents
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists
Lambertucci, Catia,Sundukova, Mayya,Kachare, Dhuldeo D.,Panmand, Deepak S.,Dal Ben, Diego,Buccioni, Michela,Marucci, Gabriella,Marchenkova, Anna,Thomas, Ajiroghene,Nistri, Andrea,Cristalli, Gloria,Volpini, Rosaria
, p. 41 - 50 (2013/10/01)
Ligands that selectively block P2X3 receptors localized on nociceptive sensory fibres may be useful for the treatment of chronic pain conditions including neuropathic pain, migraine, and inflammatory pain. With the aim at exploring the suitability of aden
Diaminopyrimidines as P2X3 and P2X2/3 antagonists
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Page/Page column 83, (2010/02/14)
Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.