3459-02-7 Usage
Type of compound
chemical compound
Industry
pharmaceutical
Form
hydrochloride salt form of 1,2,3,4-tetrahydronaphthalen-1-amine, an organic amine
Function
serotonin and norepinephrine reuptake inhibitor
Properties
potential antidepressant and analgesic properties
Use
being studied for its ability to treat a range of psychiatric and neurological disorders
Application
commonly used in the development of new medications and as a research tool to better understand the mechanisms of neurotransmitter reuptake in the brain.
Check Digit Verification of cas no
The CAS Registry Mumber 3459-02-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,5 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3459-02:
(6*3)+(5*4)+(4*5)+(3*9)+(2*0)+(1*2)=87
87 % 10 = 7
So 3459-02-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N.ClH/c11-10-7-3-5-8-4-1-2-6-9(8)10;/h1-2,4,6,10H,3,5,7,11H2;1H
3459-02-7Relevant academic research and scientific papers
Synthesis of α-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling
Kramer, S?ren
supporting information, p. 65 - 69 (2019/01/04)
A copper-catalyzed route to α-substituted, primary benzylamines by C-H functionalization of alkylarenes is described. The method directly affords the amine hydrochloride salt. Catalyst loadings down to 0.1 mol % in combination with scalability, insensitivity to air and moisture, and no need for column chromatography makes the procedure highly practical. The facile synthesis of the racemate of a blockbuster drug highlights the relevance for the development of pharmaceuticals. Preliminary mechanistic data are also included.
