34591-16-7Relevant academic research and scientific papers
Synthesis of non-nucleoside triphosphate analogues, a new type of substrates for terminal deoxynucleotidyl transferase
Arzumanov, Andrey A.,Victorova, Lyubov S.,Jasko, Maxim V.
, p. 1787 - 1793 (2000)
A series of non-nucleoside triphosphate analogues were synthesized. In place of the nucleoside fragment, substituents bearing aromatic groups were introduced; the triphosphate component was replaced at α β, or γ-positions by phosphonates. α-[2-N-(9-Fluorenylmethoxycarbonyl)aminoethylphosphonyl]-β,γ -difluoromethylenediphosphonate (IIc) revealed the best substrate properties toward terminal deoxynucleotidyl transferase.
