Synthesis of non-nucleoside triphosphate analogues, a new type of substrates for terminal deoxynucleotidyl transferase

Article abstract of DOI:10.1080/15257770008045460

A series of non-nucleoside triphosphate analogues were synthesized. In place of the nucleoside fragment, substituents bearing aromatic groups were introduced; the triphosphate component was replaced at α β, or γ-positions by phosphonates. α-[2-N-(9-Fluorenylmethoxycarbonyl)aminoethylphosphonyl]-β,γ -difluoromethylenediphosphonate (IIc) revealed the best substrate properties toward terminal deoxynucleotidyl transferase.

Full text of DOI:10.1080/15257770008045460

Nucleosides, Nucleotides and Nucleic Acids
ISSN: 1525-7770 (Print) 1532-2335 (Online) Journal homepage: http://www.tandfonline.com/loi/lncn20
Synthesis of Non-Nucleoside Triphosphate
Analogues, a New Type of Substrates for Terminal
Deoxynucleotidyl Transferase
Andrey A. Arzumanov , Lyubov S. Victorova & Maxim V. Jasko
To cite this article: Andrey A. Arzumanov , Lyubov S. Victorova & Maxim V. Jasko (2000)
Synthesis of Non-Nucleoside Triphosphate Analogues, a New Type of Substrates for Terminal
Deoxynucleotidyl Transferase, Nucleosides, Nucleotides and Nucleic Acids, 19:10-12,
1787-1793, DOI: 10.1080/15257770008045460
To link to this article: http://dx.doi.org/10.1080/15257770008045460
Published online: 17 Apr 2008.
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Date: 18 November 2015, At: 15:52