345910-97-6Relevant academic research and scientific papers
A Simple Preparation of Ketones. N-Protected α-Amino Ketones from α-Amino Acids
De Luca, Lidia,Giacomelli, Giampaolo,Porcheddu, Andrea
, p. 1519 - 1521 (2001)
matrix presented Carboxylic acids and amino acids are readily converted, under mild conditions, into the corresponding activated esters, which are reacted with Grignard/Cul reagent to give the corresponding ketones in nearly quantitative yields. The compounds were recovered substantially pure from the reaction mixtures.
