345913-09-9Relevant articles and documents
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1
Hopkins, Andrew L.,Ren, Jingshan,Milton, John,Hazen, Richard J.,Chan, Joseph H.,Stuart, David I.,Stammers, David K.
, p. 5912 - 5922 (2004)
We have used a structure-based approach to design a novel series of non-nucleoside inhibitors of HIV-1 RT (NNRTIs). Detailed analysis of a wide range of crystal structures of HIV-1 RT-NNRTI complexes together with data on drug resistance mutations has ide
Quinolone compounds for use in treating viral infections
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, (2008/06/13)
The present invention relates to quinolone compounds and their use in the treatment of viral infections.