345928-21-4

Basic information

• Product Name: 2-((4-methoxybenzyl)amino)isoindoline-1,3-dione
• Synonyms: 2-((4-methoxybenzyl)amino)isoindoline-1,3-dione
• CAS NO: 345928-21-4
• Molecular Weight: 282.299
• Mol File: 345928-21-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-((4-methoxybenzyl)amino)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-methoxybenzyl)amino)isoindoline-1,3-dione(345928-21-4)
• EPA Substance Registry System: 2-((4-methoxybenzyl)amino)isoindoline-1,3-dione(345928-21-4)

Safety Data

• Hazardous Substances Data: 345928-21-4(Hazardous Substances Data)

Upstream product

• 1875-48-5 N-aminophthalamide 
• 123-11-5 4-methoxy-benzaldehyde 
• 19279-70-0 2-((4-methoxybenzylidene)amino)isoindoline-1,3-dione 
• 85468-48-0 N-(p-methoxybenzylidene)aminophthalimide 

Downstream Products

• 5705-18-0 1-(4-methoxybenzyl)-1-phenylhydrazine 
• 530740-41-1 2-[(4-methoxy-benzyl)-phenyl-amino]-isoindole-1,3-dione 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 
• 140-69-2 4-methoxybenzylhydrazine 

Relevant articles and documents

Extending the Scope of the B(C6F5)3-Catalyzed C=N Bond Reduction: Hydrogenation of Oxime Ethers and Hydrazones

The B(C6F5)3-catalyzed hydrogenation is applied to aldoxime triisopropylsilyl ethers and hydrazones bearing an easily removable phthaloyl protective group. The C=N reduction of aldehyde-derived substrates (oxime ethers and hydrazones) is enabled by using 1,4-dioxane as the solvent known to participate as the Lewis-basic component in FLP-type heterolytic dihydrogen splitting. More basic ketone-derived hydrazones act as Lewis bases themselves in the FLP-type dihydrogen activation and are therefore successfully hydrogenated in nondonating toluene. The difference in reactivity between aldehyde- and ketone-derived substrates is also reflected in the required catalyst loading and dihydrogen pressure.

Reactions of N-Aminophthalimide With Electrophiles. II. Preparation and Properties of Araldehyde Hydrazones

N-Aminophthalimide (I) reacted with a variety of aromatic aldehydes to give the related arylideneaminophthalimides (III-X), although typical ketones such as acetone and benzophenone did not under the specific conditions employed.Catalytic reduction of benzylideneaminophthalimide (III) led to N-benzylaminophthalimide (XI), a stable acid-free precursor of benzylhydrazine.