34595-91-0

Usage

Uses

Used in Pharmaceutical Research:
2,3,5-Trimethyl-6-bromopyridine is used as a building block for the synthesis of various biologically active molecules. Its unique structure and reactivity contribute to the development of new drugs and agrochemicals, making it a valuable component in pharmaceutical research.
Used in Organic Synthesis:
In the field of organic synthesis, 2,3,5-Trimethyl-6-bromopyridine serves as a key intermediate for the production of a wide range of compounds. Its versatility in chemical reactions allows for the creation of diverse molecules with potential applications in various industries.
Used in Fine Chemicals Production:
2,3,5-Trimethyl-6-bromopyridine is utilized in the production of fine chemicals, which are high-purity chemicals used in various applications such as pharmaceuticals, agriculture, and other specialty industries. Its presence in these chemicals enhances their performance and quality.
Used in Specialty Materials Production:
This chemical compound is also employed in the creation of specialty materials, which are unique materials designed for specific applications in industries such as electronics, automotive, and aerospace. The incorporation of 2,3,5-Trimethyl-6-bromopyridine into these materials contributes to their enhanced properties and performance.
It is crucial to handle 2,3,5-Trimethyl-6-bromopyridine with care, as it may pose health and environmental hazards if not properly managed. Proper safety measures and disposal methods should be followed to minimize any potential risks associated with this chemical compound.

InChI:InChI=1/C8H10BrN/c1-5-4-6(2)8(9)10-7(5)3/h4H,1-3H3

Upstream product

• 56705-18-1 2-Amino-3,5,6-trimethylpyridine 
• 917-54-4 methyllithium 
• 117846-58-9 2,6-dibromo-3,5-dimethylpyridine 

Relevant academic research and scientific papers

IMIDAZOPYRIDINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS

The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing co

Synthesis method of 2, 3, 5-trimethyl-6-bromopyridine

The invention relates to the field of organic chemistry, in particular to a synthesis method of 2, 3, 5-trimethyl-6-bromopyridine. The method includes following steps: allowing diethyl malnoate and alkali metal to be in reaction to generate salt, and dropwise adding 2, 3 dimethyl-6-nitro-5 chloropyridine; allowing 2, 3, 5-trimethyl-6-nitropyridine to be catalyzed by Pd/C, taking methanol as a solvent, performing hydrogenation reduction and suction filtering, and concentrating filtrate to obtain 2, 3, 5-trimethyl-6-aminopyridine; enabling 2, 3, 5-trimethyl-6-aminopyridine and acid to generate salt, cooling to -9-4 DEG C, dropwise adding liquid bromine, dropwise adding a sodium nitrite water solution, adjusting pH of the solution to be alkaline after dropwise adding is completed, extracting,drying, and concentrating to obtain 2, 3, 5-trimethyl-6-bromopyridine. The method has the advantages of being mild in reaction condition, high in yield, easy-to-get in raw material, low in cost and short in process route and having industrialization prospect.

Synthetic method of 2,3,5-trimethyl-6-bromopyridine

The invention relates to the field of organic chemistry, in particular to a synthetic method of 2,3,5-trimethyl-6-bromopyridine. The synthetic method comprises the following steps: enabling diethyl malonate to react with alkali metal to generate salt, dropwise adding a toluene solution of 2,3-dimethyl-6-nitro-5-chloropyridine for condensation reaction and then decarboxylating under an acidic condition to obtain 2,3,5-trimethyl-6-nitropyridine; performing hydrogenation reduction on the 2,3,5-trimethyl-6-nitropyridine by taking methanol as a solvent under Pd/C catalysis, performing suction filtration and concentrating a filtrate to obtain 2,3,5-trimethyl-6-aminopyridine; enabling the 2,3,5-trimethyl-6-aminopyridine and acid to generate salt, cooling to 9 DEG C below zero to 4 DEG C, dropwise adding liquid bromine, dropwise adding a sodium nitrite aqueous solution after the completion of dropwise adding, regulating the pH of the solution to be alkaline after the completion of dropwise adding, extracting, drying and concentrating to obtain the 2,3,5-trimethyl-6-bromopyridine. The synthetic method provided by the invention has the benefits of being mild in reaction condition, high in yield, readily-available in raw material, lower in cost and short in process route and has industrial prospect.