34628-36-9

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 4-BENZOYL-1H-PYRROLE-2-CARBOXYLATE is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs with diverse therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, METHYL 4-BENZOYL-1H-PYRROLE-2-CARBOXYLATE is used as a versatile building block for the synthesis of a wide range of organic compounds, facilitating the creation of novel molecules with unique properties.
Used in Agricultural Chemistry:
METHYL 4-BENZOYL-1H-PYRROLE-2-CARBOXYLATE is utilized in the development of agrochemicals, potentially serving as a component in the synthesis of pesticides or other compounds that can enhance crop protection and yield.
Used in Materials Science:
In materials science, METHYL 4-BENZOYL-1H-PYRROLE-2-CARBOXYLATE is employed in the research and development of new materials, possibly contributing to advancements in areas such as polymers, coatings, or other high-performance materials due to its structural characteristics.

InChI:InChI=1/C13H17NO3/c1-17-13(16)11-7-10(8-14-11)12(15)9-5-3-2-4-6-9/h7-9,14H,2-6H2,1H3

Upstream product

• 10147-11-2 propargyl benzene 
• 39687-95-1 isocyanoacetic acid methyl ester 
• 1193-62-0 methyl Pyrrole-2-carboxylate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1443775-15-2 C₂₀H₁₉N₃O₄S 
• 1443775-87-8 C₃₀H₃₂N₂O₄ 
• 15372-84-6 4-benzoyl-1H-pyrrole-2-carboxylic acid 
• 33234-57-0 3-benzyl-1H-pyrrole 

Relevant academic research and scientific papers

The Castagnoli–Cushman reaction of bicyclic pyrrole dicarboxylic anhydrides bearing electron-withdrawing substituents

Four anhydrides of 1-(carboxymethyl)pyrrole-2-carboxylic acids bearing electron-withdrawing substituents at positions 6 or 7 of the bicyclic system have been investigated in the Castagnoli–Cushman reaction with imines. 6-Benzoyl- and 7-sulfamoyl-substitut

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4

Extracellular regulated kinase 5 (ERK5) signalling has been implicated in driving a number of cellular phenotypes including endothelial cell angiogenesis and tumour cell motility. Novel ERK5 inhibitors were identified using high throughput screening, with

High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors

The extracellular-related kinase 5 (ERK5) is a promising target for cancer therapy. A high-throughput screen was developed for ERK5, based on the IMAP FP progressive binding system, and used to identify hits from a library of 57-617 compounds. Four distinct chemical series were evident within the screening hits. Resynthesis and reassay of the hits demonstrated that one series did not return active compounds, whereas three series returned active hits. Structure-activity studies demonstrated that the 4-benzoylpyrrole-2-carboxamide pharmacophore had excellent potential for further development. The minimum kinase binding pharmacophore was identified, and key examples demonstrated good selectivity for ERK5 over p38α kinase.

Nano-copper catalysed highly regioselective synthesis of 2,4-disubstituted pyrroles from terminal alkynes and isocyanides

Nano-copper(0) stabilized on alumina prepared from Cu-Al hydrotalcite has been reported for completely regioselective synthesis of 2,4-disubstituted pyrroles from unactivated terminal aromatic/aliphatic alkynes and isocyanides. The reaction is operational

Modular preparation of diverse dipyrrolemethanes

A modular synthesis of polyfunctional dipyrrolemethanes is presented. Diverse side chains are introduced to 2-carboxypyrrole building blocks in two to four steps, resulting in a collection of substituted pyrroles that, when condensed in one step, give ris