3464-71-9

Basic information

• Product Name: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)
• Synonyms: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride);Azoniaspironortropanol Chloride;TrospiuM Chloride Related CoMpound C;(1alpha,3beta,5alpha)-3-Hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] chloride (1:1);3alpha-Hydroxynortropane-8-spiro-1'-pyrrolidinium chloride;(1R,3r,5S)-3-Hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium] chloride;Trospium Alcohol Chloride
• CAS NO: 3464-71-9
• Molecular Formula: C16H15ClO2
• Molecular Weight: 274.7421
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 3464-71-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 294-297℃
• Appearance: /
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)(CAS DataBase Reference)
• NIST Chemistry Reference: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)(3464-71-9)
• EPA Substance Registry System: Trospium Chloride Related Compound C (20 mg) (Azoniaspironortropanol chloride)(3464-71-9)

Safety Data

• Hazardous Substances Data: 3464-71-9(Hazardous Substances Data)

Usage

Uses

Trospium Chloride Related Compound C is an intermediate used for the synthesis of Trospium Chloride (T892800), an Antispasmodic, used in treatment of urinary incontinence.

Upstream product

• 110-56-5 1,4-dichlorobutane 
• 538-09-0 nortropine 

Downstream Products

• 10405-02-4 trospium chloride 

Relevant articles and documents

Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds

The present technology relates to an improved one-stage method for producing azoniaspironortropine esters such as trospium chloride by reacting an endonortropine compound with an organic dihalogen compound and an a-hydroxycarboxylic acid in the presence of a base and 1,1′ carbonyldiimidazole or 1,1′ thiocarbonyldiimidazole or thionyldiimidazole. The present technology also relates to an improved method for producing nortropan-3-one compounds or their hydrohalides (such as N-benzyltropanone hydrochloride) by reacting an amine and a protected dialdehyde with a basic aqueous solution of 1,3-acetone dicarboxylic acid.