34644-27-4Relevant academic research and scientific papers
Hydrogenolysis of Amide Acetals and Iminium Esters
Kadyrov, Renat
, p. 170 - 172 (2017/12/26)
Amide acetals and iminium esters were hydrogenated into amines under very mild reaction conditions over common hydrogenation catalysts. This finding provides a new strategy for the selective reduction of amides. The synthetic utility of this approach was demonstrated by the selective reduction of amides bearing ester and nitrile groups.
Orthoamides, XXXIV.-Syntheses with Vinylidenediamines
Kantlehner, Willi,Ivanov, Ivo C.,Mergen, Walter W.,Bredereck, Hellmut
, p. 372 - 388 (2007/10/02)
Vinylidenediamines 2a,c have been prepared from 1-ethoxyvinylamine 4 and dimethylamine or pyrrolidine, respectively.Heating of 2a and formamidinium acetate affords 4-amino-5-pyrimidinecarbonitrile (7b).Acylation of 2a with acid chlorides or acid anhydride
