34654-43-8Relevant academic research and scientific papers
One-Pot Reactions for Synthesis of 2,5-Substituted Tetrazoles from Aryldiazonium Salts and Amidines
Ramanathan, Mani,Wang, Yu-Hao,Liu, Shiuh-Tzung
, p. 5886 - 5889 (2015)
One-pot sequential reactions of aryldiazonium salts with amidines followed by the treatment of I2/KI under basic conditions provide 2,5-disubstituted tetrazoles in moderate to excellent yields. This one-pot synthesis has several advantages such as mild reaction conditions, short reaction time, convenient workup, and high yields, making this methodology practical.
5-substituted-2-2H-tetrazoleamine manufacturing method
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Paragraph 0041-0042; 0051; 0057, (2021/09/18)
The present invention is a method for producing a 5-substituted-2-aryl-2H-tetrazole that is useful as an intermediate for producing a pharmaceutical compound, and relates to a method which selectively introduces an aryl group in the 2 position.
