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4-(3-Hydroxypropylamino)-1,3-dimethyluracil, also known as HPUra, is a chemical compound belonging to the class of uracil derivatives. It possesses a molecular formula of C9H13N3O2 and has demonstrated potential pharmaceutical applications due to its antiviral and anticancer properties. HPUra's unique structure and biological activities make it a promising candidate for further research and development in the medical field.

34654-80-3

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34654-80-3 Usage

Uses

Used in Antiviral Applications:
4-(3-Hydroxypropylamino)-1,3-dimethyluracil is used as an antiviral agent for inhibiting the replication of certain viruses, such as herpes simplex virus type 1. Its ability to interfere with viral replication processes makes it a valuable compound in the development of antiviral therapies.
Used in Anticancer Applications:
In the pharmaceutical industry, 4-(3-Hydroxypropylamino)-1,3-dimethyluracil is used as an anticancer agent for its inhibitory effects on the growth of cancer cells. Its potential to target and disrupt cancer cell proliferation and survival mechanisms contributes to its significance in cancer research and treatment development.
Used in Pharmaceutical Research and Development:
4-(3-Hydroxypropylamino)-1,3-dimethyluracil is utilized as a compound of interest in pharmaceutical research and development due to its potential applications in antiviral and anticancer therapies. Its unique structure and biological activities provide a foundation for exploring new treatment options and advancing medical knowledge in these areas.

Check Digit Verification of cas no

The CAS Registry Mumber 34654-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,6,5 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 34654-80:
(7*3)+(6*4)+(5*6)+(4*5)+(3*4)+(2*8)+(1*0)=123
123 % 10 = 3
So 34654-80-3 is a valid CAS Registry Number.

34654-80-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(3-hydroxypropylamino)-1,3-dimethyl-4H-pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 4-(3-Hydroxypropylamino)-1,3-dimethyluracil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:34654-80-3 SDS

34654-80-3Relevant academic research and scientific papers

Synthesis method of urapidil medical intermediate 1,3-dimethyl-6-(3-hydroxy propyl)aminouracil

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Paragraph 0014; 0015, (2016/11/21)

A synthesis method of a urapidil medical intermediate 1,3-dimethyl-6-(3-hydroxy propyl)aminouracil includes the following steps of adding 0.61 mol of 1,3-dimethyl-6-hydroxyl uracil (2), 0.72-0.75 mol of 3-amino-1-propanol and 0.16 mol of sodium sulfite solution to a reaction container provided with a stirrer, a thermometer and a reflux condenser, controlling the stirring speed at 130-160 rpm, raising the temperature of the solution to 150-160 DEG C, reacting for 90-120 min, lowering the temperature of the solution to 60-65 DEG C, adding 230 ml of cyclohexane, conducting refluxing for 30-50 min, conducting filtering, cooling filtrate to 5-9 DEG C, standing for 30-35 h, separating out crystals, conducting filtering, washing crystals with a saline solution and acetonitrile in sequence, conducting dehydration through a dehydrating agent, and conducting recrystallization in isopropanol to obtain white crystals 1,3-dimethyl-6-(3-hydroxy propyl)aminouracil.

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