346663-56-7Relevant academic research and scientific papers
Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents
Lourenco, Maria Cristina Silva,Vicente, Felipe Rodrigues,Henriques, Maria das Gracas Muller de Oliveira,Peixoto Candea, Andre Luis,Borges Goncalves, Raoni Schroeder,Nogueira, Thais Cristina M.,de Lima Ferreira, Marcelle,Nora de Souza, Marcus Vinicius
, p. 6895 - 6898 (2007)
The present article describes a series of 21 N-(aryl)-2-thiophen-2-ylacetamides, which were synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis, and the activity expressed as the minimum inhibitory concen
Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase
Rückle, Thomas,Biamonte, Marco,Grippi-Vallotton, Tania,Arkinstall, Steve,Cambet, Yves,Camps, Montserrat,Chabert, Christian,Church, Dennis J.,Halazy, Serge,Jiang, Xuliang,Martinou, Isabelle,Nichols, Anthony,Sauer, Wolfgang,Gotteland, Jean-Pierre
, p. 6921 - 6934 (2007/10/03)
Several lines of evidence support the hypothesis that c-Jun N-terminal kinases (JNKs) play a critical role in a wide range of disease states including cell death (apoptosis)-related and inflammatory disorders (epilepsy, brain, heart and renal ischemia, ne
