Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents

DOI: 10.1016/j.bmcl.2007.09.096

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 6895 - 6898 (2007)

Update date:2022-07-30

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Authors:

Lourenco, Maria Cristina Silva

Vicente, Felipe Rodrigues

Henriques, Maria das Gracas Muller de Oliveira

Peixoto Candea, Andre Luis

Borges Goncalves, Raoni Schroeder

Nogueira, Thais Cristina M.

de Lima Ferreira, Marcelle

Nora de Souza, Marcus Vinicius

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Article abstract of DOI:10.1016/j.bmcl.2007.09.096

The present article describes a series of 21 N-(aryl)-2-thiophen-2-ylacetamides, which were synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis, and the activity expressed as the minimum inhibitory concen

Full text of DOI:10.1016/j.bmcl.2007.09.096

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Product name:2-Thiopheneacetamide, N-(4-chlorophenyl)-

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