346723-41-9

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 371-40-4 4-fluoroaniline 
• 586-76-5 4-Bromobenzoic acid 
• 6846-12-4 4-bromo-N-phenyl-benzamide 

Downstream Products

• 1931946-73-4 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)benzamide 
• 1149367-39-4 tert-butyl 4-(4-((4-fluorophenyl)carbamoyl)phenyl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

Derivatives with uracil-benzothiazole structure, preparation method of derivatives, and application of anti-HCV drugs

According to the invention, a new series of uracil-benzothiazole NS5B RdRp inhibitors are designed and synthesized; the compounds have the structure shown in a general formula (1), wherein the uracil-benzothiazole NS5B RdRp inhibitor provided by the inven

ANTIMYCOTIC TRIAZOLE COMPOUND

The invention relates to Compound (I), which is 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)-N-(4-fluorophenyl)benzamide, or a pharmaceutically acceptable salt thereof, usefu

ANTIMYCOTIC COMPOUND

This invention relates to a compound, as defined in the specification, useful in the treatment of mycoses, compositions containing it and its use in therapy.

Hypervalent iodine mediated para -selective fluorination of anilides

A metal-free method for the direct regioselective fluorination of anilides has been developed. In the presence of bis(tert-butylcarbonyloxy)iodobenzene (PhI(OPiv)2) and hydrogen fluoride-pyridine, the para-fluorination products of anilides were obtained in moderate to good yields. Because of its operational safety and the use of readily available reagents, this new procedure provides facile access to a variety of para-fluorinated anilides.

Role of Hetero-halogen (F · · · X, X = Cl, Br, and I) or homo-halogen (X · · · X, X = F, Cl, Br, and I) interactions in substituted benzanilides

A series of halogen-substituted benzanilides have been synthesized and characterized, and crystallization studies directed toward generation of polymorphs have been performed to delineate the importance of interactions involving halogens. The effect of ha