346726-05-4Relevant academic research and scientific papers
Design and synthesis of N-methylpyrimidone derivatives as HIV-1 integrase inhibitors
Wang, Yujie,Rong, Jie,Zhang, Bin,Hu, Liming,Wang, Xiaoli,Zeng, Chengchu
, p. 735 - 741 (2015/02/19)
A series of novel β-diketo derivatives which combined the virtues of dihydroxypyrimidine carboxamide derived from the evolution of DKA and polyhydroxylated aromatics moieties, were designed and synthesized as potential HIV-1 integrase (IN) inhibitors and
Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors
Hu, Yueqing,Zhang, Jun,Chandrashankra, Oormila,Ip, Fanny C.F.,Ip, Nancy Y.
, p. 676 - 683 (2013/02/25)
Four series of novel heterodimers comprised of donepezil and huperzine A (HupA) fragments were designed, synthesized, and evaluated in search of potent acetylcholinesterase (AChE) inhibitors as potential therapeutic treatment for Alzheimer's disease. Hete
Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor
Yang, Leifu,Xu, Xuemei,Huang, Yali,Zhang, Bin,Zeng, Chengchu,He, Hongqiu,Wang, Cunxin,Hu, Liming
supporting information; experimental part, p. 5469 - 5471 (2010/12/24)
(E)-N-[3-(4-Cinnamoylpiperazin-1-yl)propyl]-3,4-dihydroxybenzamide and (E)-N-[3-(4-cinnamoylpiperazin-1-yl)propyl]-3,4,5-trihydroxybenzamide were designed and synthesized as potential HIV-1 integrase inhibitors and evaluated their inhibition to the strand
