34690-52-3Relevant academic research and scientific papers
Functionalized pyrazoles as agents in C-C cross-coupling reactions
Pejic, Marijana,Popp, Sebastian,Bolte, Michael,Wagner, Matthias,Lerner, Hans-Wolfram
, p. 83 - 97 (2014/06/09)
The 1-tetrahydropyranyl-(THP-)protected pyrazoles 4-R-pz(THP) (R=pinacolatoboryl=Bpin (3a(THP)), Me3Si (4a(THP)), Me3Sn (5a(THP)), and 4-R-3,5-Ph2pz (R=Bpin (3b(THP)), Me3Si (4b(THP)), Me3Sn (5b(THP))
Synthesis and Reactions of 3,4-Bis(trimethylsilyl)-1-pyrazolines
Birkofer, Leonhard,Kuehn, Thomas
, p. 2293 - 2299 (2007/10/02)
1,3-Dipolar cycloaddition of diazomethane to the trans-1,2-bis(trimethylsilyl)ethenes 1 a-c affords the trans-3,4-bis(trimethylsilyl)-1-pyrazolines 2 a-c.Thermolysis of 2 a-c yields stereospecifically the trans-1,3-bis(trimethylsilyl)propenes 7 b, c and d.The pyrazoline 2 c is dehalogenated with Zn to give 3(5),4-bis(trimethylsilyl)pyrazole (8).Reaction of 2 a with tetrachloro-o-benzoquinone and of 2 b and c with methanolic NaOH leads to dehydrosilylation and elimination of halogenotrimethylsilane, respectively, with formation of the pyrazoles 9 - 11. 10 and 11 can be desilylated by treatment with acid to yield 12 and 13, resp.
