34698-20-9Relevant academic research and scientific papers
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells
Landi, Martina,Catelani, Giorgio,D'Andrea, Felicia,Ghidini, Eleonora,Amari, Gabriele,Paola, Puccini,Bianchi, Nicoletta,Gambari, Roberto
experimental part, p. 745 - 754 (2009/09/27)
A series of carbamides derived from 1,2:5,6-di-O-isopropylidene-d-gluco- (1) and d-allofuranose (3) as well as their 5,6-O-deprotected analogues (2 and 4) and methyl 3,4-O-isopropylidene-α- and β-d-galactopyranosides (5 and 6) have been prepared in order to evaluate their ability to induce erythroid differentiation of human erythroleukemic K562 cells. Twenty out of 51 carbamides tested exhibit an appreciable activity as inducers of erythroid differentiation and have been fully characterized and described.
Use of Ferric Chloride in Carbohydrate Reactions: Part III-Reaction of Methyl Glycosides and Methyl 6-O-Tosyl Glycosides with Ferric Chloride-Acetone
Dasgupta, F.,Singh, P. P.,Srivastava, H. C.
, p. 1056 - 1059 (2007/10/02)
Ferric chloride-acetone has been used for the preparation of O-isopropylidene derivates of methyl glycosides and methyl 6-O-tosyl glycosides.Using this reagent 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose, methyl 4,6-O-isopropylidene-α-D-glucopyranoside, methyl 2,3-O-isopropylidene-α-D-galactopyranoside, methyl 4,6-O-isopropylidene-α-D-galactopyranoside, 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose,1,2:3,5-di-O-isopropylidene-6-O-tosyl-α-D-glucofuranose, 1,2:3,4-di-O-isopropylidene-6-O-tosyl-α-D-galactopyranose and methyl 3,4-O-isopropylidene-6-O-tosyl-α-D-galactopyranoside have been prepared.Inhibition by tosyl group in the hydrolysis of the glycosidic function has been rationalised.
