34701-98-9

Usage

Uses

Used in Sunscreen and Cosmetic Products:
2-chloro-4'-phenylbenzophenone is used as a UV filter for its ability to absorb UVB and short UVA rays, providing protection against skin damage and sunburn. However, due to concerns about its safety and environmental impact, some regulatory bodies have restricted its use, and there is ongoing research to find alternative UV filters with better safety profiles.

Upstream product

• 92-52-4 biphenyl 
• 609-65-4 o-chlorobenzoyl chloride 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 19063-39-9 3-phenyl-9H-fluoren-9-one 
• 103049-25-8 3-biphenyl-4-yl-3-(2-chloro-phenyl)-2-(4-chloro-phenyl)-acrylonitrile 
• 34974-11-3 4-Diphenylyl-phenyl-o-chlorphenylcarbinol 
• 79446-82-5 3-Biphenyl-4-yl-3-(2-chloro-phenyl)-3-hydroxy-propionic acid ethyl ester 
• 42074-52-2 4-Diphenylyl-phenyl-o-chlorphenyl-methylchlorid 
• 79446-89-2 3-Biphenyl-4-yl-3-(2-chloro-phenyl)-3-hydroxy-propionic acid 
• 79446-89-2 3-Biphenyl-4-yl-3-(2-chloro-phenyl)-3-hydroxy-propionic acid 
• 79446-89-2 (R)-3-Biphenyl-4-yl-3-(2-chloro-phenyl)-3-hydroxy-propionic acid 

Relevant academic research and scientific papers

Crystal structures of two 4-phenylbenzophenones

Two 4-phenylbenzophenones (I) and (II) are synthesized via Friedel-Crafts reactions. There are four crystallographically independent molecules with different conformations in the crystal structure of [1,1′-biphenyl]-4- yl(2-chlorophenyl)methanone (I). Crystals are orthorhombic, Pca21, C19H13ClO, a = 13.699(3) A, b = 8.9385(17) A, c = 46.836(9) A; V = 5735(2) A3, Z = 16, d x = 1.356 g/cm3. Torsion angles between the biphenyl rings are between 28.5 and 30.8. Several C-H.O and C-H.Cl hydrogen bonds and weak π-π stacking contacts consolidate the crystal. Crystals of [1,1′-biphenyl]-4- yl(3-methoxyphenyl)methanone (II) are orthorhombic, Pbca, C20H 16O2, a = 7.8179(15) A, b = 16.003(3) A, c = 23.345(5) A; V = 2920.7(10) A3, Z = 8, d x = 1.311 g/cm3. The torsion angle between the biphenyl rings is 28.1 and C-H.O hydrogen bonds are observed in compound (II).

Cobalt-Catalyzed Asymmetric Hydrogenation of 1,1-Diarylethenes

Highly enantioselective cobalt-catalyzed hydrogenation of 1,1-diarylethenes was developed by using bench-stable chiral oxazoline iminopyridine-cobalt complexes as precatalysts. A unique o-chloride effect was observed to achieve high enantioselectivity. Easy removal as well as further transformations of the chloro group make this protocol a potentially useful alternative to synthesize various chiral 1,1-diarylethanes. This process can be successfully performed under 1 atm of hydrogen at room temperature on gram scale.

Insertion of arynes into carbon-halogen σ-bonds: Regioselective acylation of aromatic rings

Arynes were found to insert into carbon-halogen σ-bonds of various acid halides, enabling acyl and halogen moieties to be introduced simultaneously into adjacent positions of aromatic rings. The Royal Society of Chemistry.