34722-37-7

Basic information

• Product Name: 4-METHOXYBENZYL THIOACETIC ACID
• Synonyms: BUTTPARK 35\01-99;4-METHOXYBENZYL THIOACETIC ACID
• CAS NO: 34722-37-7
• Molecular Formula: C₁₀H₁₂O₃S
• Molecular Weight: 212.27
• Mol File: 34722-37-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 366.9°Cat760mmHg
• Flash Point: 175.7°C
• Appearance: /
• Density: 1.238g/cm³
• Vapor Pressure: 4.97E-06mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 4-METHOXYBENZYL THIOACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXYBENZYL THIOACETIC ACID(34722-37-7)
• EPA Substance Registry System: 4-METHOXYBENZYL THIOACETIC ACID(34722-37-7)

Safety Data

• Hazardous Substances Data: 34722-37-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O3S/c1-13-9-4-2-8(3-5-9)6-14-7-10(11)12/h2-5H,6-7H2,1H3,(H,11,12)

Upstream product

• 65051-28-7 1-(carboethoxy)-1-(4-methoxybenzylthio)methane 
• 6258-60-2 p-methoxybenzylmercaptan 
• 79-08-3 bromoacetic acid 
• 68-11-1 mercaptoacetic acid 
• 824-94-2 p-methoxybenzyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 105-13-5 4-Methoxybenzyl alcohol 
• 79-11-8 chloroacetic acid 

Downstream Products

• 28203-60-3 ((4-methoxylbenzyl)sulfonyl)acetic acid 
• 28203-55-6 ((4-methoxybenzyl)sulfinyl)acetic acid 
• 34722-44-6 methyl 2-((4-methoxybenzyl)thio)acetate 
• 917887-11-7 tert-butyl (4-{(2R,3R)-1-(4-chlorophenyl)-3-[(4-methoxybenzyl)thio]-4-oxoazetidin-2-yl}phenoxy)acetate 
• 858104-46-8 tert-butyl (4-{(1R)-1-[(4-fluorophenyl)amino]-2-[(4-methoxybenzyl)thio]-3-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]propyl}phenoxy)acetate 
• 858104-47-9 (3R,4R)-1-(4-fluorophenyl)-3-(4-methoxybenzylsulphanyl)-4-[4-(t-butoxycarbonylmethoxy)phenyl]azetidin-2-one 
• 1609008-06-1 E-acetic acid 2-acetoxy-4-[2-(4-methoxyphenylmethanesulfinyl)vinyl]phenyl ester 
• 1609007-98-8 E-acetic acid 2-acetoxy-4-[2-(4-methoxyphenylmethanesulfonyl)vinyl]phenyl ester 
• 592542-51-3 4-methoxy-3-nitrophenylmethanesulfonyl acetic acid 
• 858104-45-7 (4S)-3-{2-[(4-methoxyphenyl)methylthio]acetyl}-4-phenyl-1,3-oxazolidin-2-one 
• 1011290-96-2 1-(2-(4-methoxybenzylthio)acetyl)-2-methyl-3-phenylisothiourea 
• 1011291-07-8 dimethyl [2-((4-methoxybenzyl)thio)acetyl]carbonodithioimidate 
• 1011291-00-1 1-(4-fluorobenzyl)-3-(2-(4-methoxybenzylthio)acetyl)-2-methylisourea 
• 65051-30-1 p-methoxybenzyl-sulphinyl-acetohydroxamic acid 

Relevant articles and documents

Styryl sulfones compound, its preparation method and its use as neuroprotective agents

The application relates to design of a novel molecule with ester group substituted by sulfone group by using a caffeic acid phenethyl ester (CAPE) with neuroprotective activity extracted from natural propolis as a primer according to bioisosterism principle and hydrogen-bond interaction theory; and the molecule has a structural general formula I, and the definition of each group is shown in the claims. The invention also relates to compound in vitroantioxidation capability evaluation, neuroprotective activity evaluation on cell level and traverse blood brain barrier ability evaluation. Activity evaluation results show that the synthesized novel compound has enhanced neuroprotective activity and can easily traverse the blood brain barrier, thus becoming a novel neuroprotective agent for treating neurodegenerative diseases.

E-3,4-di-calcium method for preparing vinyl sulfoxide compound thereof as a neuroprotective pharmaceutical application

The invention relates to an application of E-3,4-dihydroxyphenylvinyl sulfoxide represented by the formula I in preparation of nerve protection drugs for treating neurodegenerative diseases, wherein the definitions of each group in the formula I are listed in the description. The invention also relates to a preparation method of E-3,4-dihydroxyphenylvinyl sulfoxide.

Synthesis and antioxidant activity of 1,4-[Bis(3-arylmethanesulfonyl pyrrolyl and pyrazolyl)]benzenes

A variety of (1,4-phenylene)bis(arylmethanesulfonylpyrroles and pyrazoles) were prepared by the cycloaddition of 1,3-dipolar reagents, tosylmethyl isocyanide and diazomethane to the Michael acceptor, 1,4-bis(E)-2- ((arylmethanesulfonyl)vinyl)benzene. All the compounds were evaluated for antioxidant activity. Amongst the tested compounds, one of them displayed excellent radical scavenging activity in all the three methods evaluated when compared with the standard Ascorbic acid. On the other hand, 1,4-(bis(3-arylmethanesulfonyl)-1H-pyrazol-4-yl)benzenes exhibited comparatively higher antioxidant activity than 1,4-(bis(3-arylmethanesulfonyl)-1H-pyrrol-4- yl) benzenes. In general, it was observed that compounds having methoxy substitutent on aromatic ring displayed greater antioxidant activity than the other substituents. ?2014 Sociedade Brasileira de Qui?mica.