347406-07-9

Basic information

• Product Name: N-(4-bromobenzyl)-2-methylpropan-1-amine
• CAS NO: 347406-07-9
• Molecular Formula: C₁₁H₁₆BrN
• Molecular Weight: 242.1554
• Mol File: 347406-07-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 283°C at 760 mmHg
• Flash Point: 125°C
• Density: 1.228g/cm³
• Vapor Pressure: 0.00324mmHg at 25°C
• Refractive Index: 1.53
• CAS DataBase Reference: N-(4-bromobenzyl)-2-methylpropan-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromobenzyl)-2-methylpropan-1-amine(347406-07-9)
• EPA Substance Registry System: N-(4-bromobenzyl)-2-methylpropan-1-amine(347406-07-9)

Safety Data

• Hazardous Substances Data: 347406-07-9(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 108-18-9 diisopropylamine 
• 873-75-6 4-bromobenzenemethanol 
• 78-81-9 isobutylamine 

Relevant articles and documents

NEW SULFONAMIDE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative with cholesterol lowering effect, neutral fat reduction effect, and FXR agonist effect that is expected to be effective for treatment of NAFLD and NASH, or a salt thereof, and pharmaceutical compositions containing them. SOLUTION: The invention provides: a new sulfonamide derivative, a typical example of which is 6-{4-[(N-isobutylphenylsulfonamide)methyl]-2-methoxyphenyl}-2-naphthalenecarboxylic acid (general formula (5) in the figure); a pharmaceutically acceptable salt thereof; and pharmaceutical compositions containing them. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

In Situ Oxidation-Imine Formation-Reduction Routes from Alcohols to Amines

(matrix presented) Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.