34756-16-6

Basic information

• Product Name: 5-Methylfuran-2-propionaldehyde
• Synonyms: 5-methylfuran-2-propionaldehyde;3-(Methylfuryl)propanal;3-(5-methyl-2-furyl)propanal;2-Methyl-5-(2-formylethyl)furan;2-Methylfuran-5-propanal;3-(5-Methyl-2-furanyl)propanal;5-Methylfuran-2-propanal;3-(5-Methylfuran-2-yl)propionaldehyde
• CAS NO: 34756-16-6
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.16
• EINECS: 252-190-1
• Mol File: 34756-16-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 58°C/4mmHg(lit.)
• Flash Point: 75.1 °C
• Appearance: /
• Density: 1.022 g/cm³
• Vapor Pressure: 0.62mmHg at 25°C
• Refractive Index: 1.4750 to 1.4820
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 5-Methylfuran-2-propionaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methylfuran-2-propionaldehyde(34756-16-6)
• EPA Substance Registry System: 5-Methylfuran-2-propionaldehyde(34756-16-6)

Safety Data

• Hazardous Substances Data: 34756-16-6(Hazardous Substances Data)

Usage

Uses

3-(5-Methylfuran-2-yl)propanal can be used for various organic reagents.

InChI:InChI=1/C8H10O2/c1-7-4-5-8(10-7)3-2-6-9/h4-6H,2-3H2,1H3

Upstream product

• 17162-95-7 3-(5-methyl-2-furanyl)-1-propanol 
• 67-68-5 dimethyl sulfoxide 
• 534-22-5 2-methylfuran 
• 107-02-8 acrolein 

Downstream Products

• 60858-07-3 2-hex-3-enyl-5-methyl-furan 

Relevant articles and documents

Halogen Bond-Catalyzed Friedel?Crafts Reactions of Furans Using a 2,2’-Bipyridine-Based Catalyst

A halogen bond donor based on a 2,2’-bipyridine framework has been synthesized, and used to catalyze Friedel?Crafts reactions of furans. Electrophiles used successfully in these reactions included various enones, an aldehyde, and a carboxylic acid anhydride. The yields of the reactions were generally good using a moderate catalyst loading (0.025 or 0.1 equiv.) at a relatively low temperature (room temp. or 50 °C) in acetonitrile. The catalyst used was designed with a biaryl scaffold so that if it indeed proved to be an efficient halogen bond donor organocatalyst, an enantioenriched version of it could potentially serve as a stereoselective catalyst. (Figure presented.).

Photooxygenation of azidoalkyl furans: Catalyst-free triazole and new endoperoxide rearrangement

Photooxygenation of azidoalkyl furans has revealed both a novel triazole formation method and a unique endoperoxide rearrangement. The key step of this method is a 3 + 2 cycloaddion of the azide to the endoperoxide intermediate. The reduction of the peroxide bond and two subsequent C-C bond cleavages provide a triazole having a newly formed carboxylic acid functionality. The reactions are clean and efficient with yields ranging from 60% to 90%.

The condensation of carbonyl compounds with electron-rich arenes: Mercury, thallium, gold or a proton?

Gold(III) chloride, mercury(II) perchlorate, thallium(III) perchlorate and p-toluenesulfonic acid were found to efficiently catalyze the condensation of two furans with aldehydes or acetone. The olefinic unit of α,β- unsaturated carbonyl compounds reacts faster than the carbonyl group, other olefins do not react selectively. The first (addition) step is rate-limiting, the second (substitution) step is much faster.