3476-68-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Methyl-4(1H)-quinazolinone is used as a building block for the synthesis of bioactive compounds, particularly in the development of new drugs and agrochemicals. Its unique structure and properties contribute to its versatility in creating potential therapeutic agents.
Used in Drug Synthesis:
1-Methyl-4(1H)-quinazolinone is used as an intermediate in the production of potential drugs, leveraging its chemical properties to facilitate the creation of novel pharmaceutical compounds.
Used in Preclinical Research:
1-Methyl-4(1H)-quinazolinone is used as a subject of preclinical studies to investigate its therapeutic potential, including its anticonvulsant and analgesic effects, which may lead to the development of new treatments for various conditions.

InChI:InChI=1/C9H8N2O/c1-11-6-10-9(12)7-4-2-3-5-8(7)11/h2-6H,1H3

Upstream product

• 16347-97-0 4-phenoxy-quinazoline 
• 80-48-8 methyl p-toluene sulfonate 
• 119-68-6 N-Methylanthranilic acid 
• 77287-34-4 formamide 
• 96630-56-7 1-methyl-4-methylsulfanyl-quinazolinium; iodide 
• 7505-81-9 2-methylaminobenzamide 
• 91-56-5 indole-2,3-dione 
• 122-51-0 orthoformic acid triethyl ester 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 5190-68-1 4-chloroquinazoline 
• 88267-66-7 2-ethoxycarbonyl-1-methyl-4(1H)-quinazolinone 
• 88267-78-1 2-carboxy-1-methyl-4(1H)-quinazolinone 

Downstream Products

• 7505-81-9 2-methylaminobenzamide 

Relevant academic research and scientific papers

Synthesis of 1-substituted 4(1H)-quinazolinones under solvent-free conditions

(Chemical Equation Presented) Heating a mixture of 2-(N-alkylamino)benzoic acids, triethyl orthoformate, and ammonium acetate under solvent-free conditions generated 1-substituted 4(1H)- quinazolinones in 73-99% yields. Moreover, a possible reaction pathway was proposed. Copyright Taylor & Francis Group, LLC.

THE REACTION OF 2,4,6-TRIS(TRIMETHYLSILOXY)-1,3,5-TRIAZINE WITH CHLOROCARBENIUM IONS: A NEW ACCESS TO 1-OXA-3-AZABUTATRIENIUM AND 2-AZAALLENIUM SALTS

Chlorocarbenium salts 2a-d of the Vilsmeier-Arnold type react with the silylated isocyanuric acid 3 to give 1-oxa-3-azabutatrienium salts 1 under mild conditions.From reactions of diarylchloromethenium salts 2h-l with 3 and ketones or tertiary carboxamide

Composes Sulfures Heterocycliques. CII. Action de l'hydroxylamine sur les dihydro-1,2 benzothiazine-3,1 thiones-4

Hydroxylamine reacts with 1-alkyl-1,2-dihydro-3,1-benzothiazine-4-thiones (1), giving 1-alkyl-3-hydroxy-2,3-dihydro-1H-quinazoline-4-thiones (2).The same reagent, in neutral medium, converts 1-aryl-1,2-dihydro-3,1-benzothiazine-4-thiones (3) into 1-aryl-4

Studies on 4(1H)-Quinazolinones. III. Some Derivatizations of 2-Ethoxycarbonylalkyl-1-substitued-4-(1H)-quinazolinones

Reactions of 2-(substitued-amino)benzamide (1) with ethyl chloroformylformate (2), ethyl chloroformylacetate (3), and ethyl 2-chloroformylpropionate (4) gave 1-substituted 4(1H)-quinazolinones (5,6,and 7, respectively) having an ethoxycarbonyl group on th