3476-69-5 Usage
Classification
Heterocyclic compound
Contains a ring structure with both carbon and nitrogen atoms
Subclass
Quinazolinone class of compounds
A specific type of heterocyclic compound with potential pharmacological properties
Pharmacological properties
Potent inhibitor of platelet-derived growth factor receptor (PDGFR) and c-kit
PDGFR and c-kit are important in cell proliferation and survival, making 1-Propylquinazolin-4(1H)-one a potential therapeutic agent
Potential applications
Treatment of various diseases, including cancer and cardiovascular diseases
Due to its ability to inhibit PDGFR and c-kit, it may be useful in treating diseases characterized by abnormal cell growth or proliferation
Research potential
Promising candidate for further research in drug discovery and development
Its chemical structure and properties make it a valuable subject for continued investigation in the field of medicinal chemistry
Check Digit Verification of cas no
The CAS Registry Mumber 3476-69-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,7 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3476-69:
(6*3)+(5*4)+(4*7)+(3*6)+(2*6)+(1*9)=105
105 % 10 = 5
So 3476-69-5 is a valid CAS Registry Number.
3476-69-5Relevant academic research and scientific papers
Synthesis of 1-substituted 4(1H)-quinazolinones under solvent-free conditions
Wang, Yao,Zhang, Mei,Cao, Shengli,Lin, Huihui,Gao, Man,Li, Zhongfeng
, p. 2715 - 2727 (2012/07/14)
(Chemical Equation Presented) Heating a mixture of 2-(N-alkylamino)benzoic acids, triethyl orthoformate, and ammonium acetate under solvent-free conditions generated 1-substituted 4(1H)- quinazolinones in 73-99% yields. Moreover, a possible reaction pathway was proposed. Copyright Taylor & Francis Group, LLC.
