3477-69-8

Basic information

• Product Name: 4-Pyridinecarboxylicacid, 2-[(2,4-dihydroxyphenyl)methylene]hydrazide
• Synonyms: 4-Pyridinecarboxylicacid, [(2,4-dihydroxyphenyl)methylene]hydrazide (9CI); Hydrazine, 1-(2,4-dihydroxybenzylidene)-2-isonicotinoyl-(5CI); Isonicotinic acid, (2,4-dihydroxybenzylidene)hydrazide (7CI,8CI);2,4-Dihydroxybenzaldehyde isonicotinoylhydrazone; 2,4-Dihydroxybenzaldehydeisonicotinylhydrazone; NSC 51353; Resorcinal isonicotinoylhydrazone
• CAS NO: 3477-69-8
• Molecular Formula: C13H11 N3 O3
• Molecular Weight: 257.249
• Mol File: 3477-69-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 392.2°Cat760mmHg
• Flash Point: 191°C
• Density: 1.495g/cm³
• CAS DataBase Reference: 4-Pyridinecarboxylicacid, 2-[(2,4-dihydroxyphenyl)methylene]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxylicacid, 2-[(2,4-dihydroxyphenyl)methylene]hydrazide(3477-69-8)
• EPA Substance Registry System: 4-Pyridinecarboxylicacid, 2-[(2,4-dihydroxyphenyl)methylene]hydrazide(3477-69-8)

Safety Data

• Hazardous Substances Data: 3477-69-8(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Relevant articles and documents

Effective methods for the synthesis of hydrazones, quinazolines, and Schiff bases: Reaction monitoring using a chemometric approach

Synthesis of hydrazones (1a-4a and 1b-4b), quinazolines (3c·MeOH and 3d·MeOH), and hydrazone-Schiff bases (4c and 4d) is achieved by combining suitable aldehydes (2,3- or 2,4-dihydroxybenzaldehyde) with four hydrazides (isonicotinic, nicotinic, and 2- or

Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

A library of acylhydrazone iron chelators was synthesized and tested for its ability to inhibit the growth of a chloroquine-resistant strain of Plasmodium falciparum. Some of these new compounds are significantly more active than desferrioxamine DFO, the