34776-73-3

Basic information

• Product Name: 2-(Chloromethyl)-5-methylthiophene
• Synonyms: 2-(Chloromethyl)-5-methylthiophene;5-Methyl-2-thienylchloromethane
• CAS NO: 34776-73-3
• Molecular Formula: C₆H₇ClS
• Molecular Weight: 146.64
• Product Categories: Thiophens
• Mol File: 34776-73-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 83-84 °C(Press: 14 Torr)
• Appearance: /
• Density: 1.193±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-(Chloromethyl)-5-methylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Chloromethyl)-5-methylthiophene(34776-73-3)
• EPA Substance Registry System: 2-(Chloromethyl)-5-methylthiophene(34776-73-3)

Safety Data

• Hazardous Substances Data: 34776-73-3(Hazardous Substances Data)

Usage

General Description

2-(Chloromethyl)-5-methylthiophene is an organic compound that belongs to the class of thiophenes, which are aromatic heterocycles containing a sulfur atom. It is characterized by the presence of a chlorine group and a methyl group attached to the thiophene ring. 2-(Chloromethyl)-5-methylthiophene is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and materials. Its chemical properties make it a valuable intermediate in the production of a wide range of fine chemicals, making it an important ingredient in many industries. Additionally, 2-(Chloromethyl)-5-methylthiophene is also investigated for its potential biological activities and medicinal applications.

Upstream product

• 554-14-3 2-Methylthiophene 
• 50-00-0 formaldehyd 
• 63826-59-5 5-methyl-2-thiophenemethanol 
• 13679-70-4 5-methylthiophene-2-carboxaldehyde 

Relevant articles and documents

DETECTION OF 2,5-DIMETHYLENE-2,5-DIHYDROTHIOPHENE AND THIOPHENORADIALENE

The reactive species 2,5-dimethylene-2,5-dihydrothiophene and thiophenoradialene have been detected for the first time.The method of HCl elimination has proved to be a generally applicable method for generating heterocyclic xylylenes and radialenes.

MUSCARINIC AGONISTS AS NON-STEROIDAL AND NON-OPIOID ANALGESICS AND METHODS OF USE THEREOF

Novel Gi/o-biased muscarinic agonists selectively activate only one specific signaling pathway and are novel pharmacophores for development of new painkillers (analgesics). Methods of making and using these agonists are also described.

Palladium-catalyzed regioselective allylation of five-membered heteroarenes with allyltributylstannane

Palladium-catalyzed allylation reactions of 2-(chloromethyl)thiophenes, 2-(chloromethyl)furans, and N-protected 2-(chloromethyl)-1H-pyrroles with allyltributylstannane were described in this study. This type of allylation reaction regioselectively occurred on the heteroarene rings to produce allylated dearomatization products or allylated heteroarenes with satisfactory yields.