63826-59-5Relevant academic research and scientific papers
HYDROXYMETHYLATION OF METHYLSUBSTITUTED PYRROLE, THIOPHENE, AND FURAN IN THE PRESENCE OF H+ CATION EXCHANGERS
Iovel', I. G.,Gol'dberg, Yu. Sh.,Shimanskaya, M. V.
, p. 1316 - 1318 (2007/10/02)
In the reaction of formalin with the 2,5-dimethyl derivatives of pyrrole, thiophene, and furan in the presence of the sulfo cation exchanger Amberlyst 15 electrophilic substitution takes place at various positions of the rings with the formation of 2,5-dimethyl-1-hydroxymethylpyrrole, 1,3-dioxacycloheptano-2,5-dimethylthiophene (an intermediate in the formation of which is 2,5-dimethyl-3,4-dihydroxymethylthiophene), and 2,5-hexanedione respectively.Bis(5-methyl-2-thienyl)methane was obtained from 2-methylthiophene.
A NEW REACTION IN COMPOUNDS OF THE FURAN SERIES
Kharchenko, V. G.,Gubina, T. I.,Markushina, I. A.
, p. 343 - 347 (2007/10/02)
2,5-Dialkylfurans and alcohols, ketones, and esters of the furan series react with hydrogen sulfide under the conditions of acid catalysis and are converted into the corresponding analogs of the thiophene series.A possible reaction mechanism is discussed.
