347841-46-7 Usage
Uses
Used in Pharmaceutical Research and Analysis:
URSODEOXYCHOLIC-2,2,4,4-D4 ACID is used as an internal standard for the quantification of UDCA in pharmaceutical research and analysis. It aids in the accurate measurement of UDCA levels by GCor LC-MS, ensuring reliable and precise results.
Used in Cholelithogenic Applications:
URSODEOXYCHOLIC-2,2,4,4-D4 ACID is used as an anticholelithogenic agent, which means it helps prevent the formation of gallstones. Its properties make it a useful compound in the development of treatments for conditions related to bile acid imbalances and gallstone formation.
Used in Bile Acid Quantification:
URSODEOXYCHOLIC-2,2,4,4-D4 ACID is used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry. This application allows for the efficient and accurate measurement of bile acid levels in various biological samples, which is crucial for understanding and managing conditions related to bile acid metabolism.
Used in the Treatment of Primary Biliary Cirrhosis:
Formulations containing URSODEOXYCHOLIC-2,2,4,4-D4 ACID have been used in the treatment of primary biliary cirrhosis, a chronic liver disease. Its presence in these formulations contributes to the therapeutic effects of the treatment, helping to manage the symptoms and progression of the disease.
Check Digit Verification of cas no
The CAS Registry Mumber 347841-46-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,7,8,4 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 347841-46:
(8*3)+(7*4)+(6*7)+(5*8)+(4*4)+(3*1)+(2*4)+(1*6)=167
167 % 10 = 7
So 347841-46-7 is a valid CAS Registry Number.
347841-46-7Relevant academic research and scientific papers
Syntheses with stable isotopes: synthesis of deuterium and 13C labeled bile acids
Hachey,Szczepanik,Berngruber,Klein
, p. 703 - 719 (2007/10/16)
A series of 5β cholanic acids labeled with deuterium in the A ring were prepared by exchange labeling of the corresponding ketone by column chromatography on deuterated alumina. Factors affecting yield and labeling efficiency are discussed. 5β Cholanic acids labeled with 13C in the carboxyl position were prepared by treatment of the corresponding 23 chloro 24 norcholane with sodium cyanide 13C followed by alkaline hydrolysis of the nitrile. The intermediates in the synthesis were characterized by high resolution NMR spectroscopy. Mass spectra are also reported for the 13C labeled products.
