348-39-0 Usage
Uses
Used in Pharmaceutical Industry:
2H-INDAZOLE, 6-FLUORO-2-METHYLis used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure, featuring a fluorine and methyl group, allows for the creation of novel drug candidates with potential therapeutic applications.
Used in Research Applications:
In the field of scientific research, 2H-INDAZOLE, 6-FLUORO-2-METHYLserves as a valuable compound for studying the effects of structural modifications on the properties and activities of indazole-based molecules. This can lead to a better understanding of their potential uses and mechanisms of action in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 348-39-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 348-39:
(5*3)+(4*4)+(3*8)+(2*3)+(1*9)=70
70 % 10 = 0
So 348-39-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7FN2/c1-11-5-6-2-3-7(9)4-8(6)10-11/h2-5H,1H3
348-39-0Relevant academic research and scientific papers
Direct N-Alkylation and Kemp Elimination Reactions of 1-Sulfonyl-1H-Indazoles
Tang, Meng,Chu, Bingjie,Chang, Xiaowei
, p. 2109 - 2116 (2018/07/31)
The reactions of 1-sulfonyl-1H-indazoles under basic conditions are discussed, and the direct N-alkylation and Kemp elimination reactions of these compounds are reported. A series of 2-(p-tosylamino)benzonitriles and N-alkyl indazoles were prepared in good yields. Moreover, the 2-(p-tosylamino)benzonitriles could be transformed into a diverse range of important derivatives in a one-pot reaction. This method was successfully applied to the total syntheses of quindolinone and cryptolepinone; quindolinone was prepared in a one-pot reaction from 1-sulfonyl-1H-indazole.
