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6-fluoro-N-(4-nitrophenyl)benzo[d]thiazol-2-amine is a chemical compound with the molecular formula C14H8FN3O2S. It is a derivative of benzothiazole, a heterocyclic compound consisting of a benzene ring fused to a thiazole ring. The molecule features a fluorine atom at the 6th position, a nitro group attached to the 4-nitrophenyl group, and an amino group at the 2nd position. 6-fluoro-N-(4-nitrophenyl)benzo[d]thiazol-2-amine is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly as a building block for the development of new drugs. Its unique structure and functional groups make it an interesting target for researchers in the field of medicinal chemistry, as it can be further modified to create a variety of biologically active molecules.

348-42-5

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348-42-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 348-42-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 348-42:
(5*3)+(4*4)+(3*8)+(2*4)+(1*2)=65
65 % 10 = 5
So 348-42-5 is a valid CAS Registry Number.

348-42-5Downstream Products

348-42-5Relevant academic research and scientific papers

Postsynthetic modification of IRMOF-3 with a copper iminopyridine complex as heterogeneous catalyst for the synthesis of 2-aminobenzothiazoles

Liu, Jie,Zhang, Xiaobin,Yang, Jin,Wang, Lei

, p. 198 - 203 (2014/03/21)

A copper iminopyridine complex has been immobilized on to a metal-organic framework (MOF) through postsynthetic modification of IRMOF-3. The modified MOFs were fully demonstrated by using a variety of methods, and the structural integrity of the modified

DDQ-promoted C-S bond formation: Synthesis of 2-aminobenzothiazole derivatives under transition-metal-, ligand-, and base-free conditions

Wang, Rui,Yang, Wen-Juan,Yue, Liang,Pan, Wei,Zeng, Hong-Yao

experimental part, p. 1643 - 1648 (2012/08/07)

A transition-metal-free method for the intramolecular S-arylation of o-halobenzothiaoureas via DDQ-mediated leading to the 2-aminobenzothiazole derivatives is reported. The reactions are performed at room temperature under ligand- and base-free conditions with good to excellent yields. Georg Thieme Verlag Stuttgart · New York.

Synthesis of 2-aminobenzothiazole via FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water

Ding, Qiuping,Cao, Banpeng,Liu, Xianjin,Zong, Zhenzhen,Peng, Yi-Yuan

supporting information; experimental part, p. 1607 - 1610 (2010/12/19)

An FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water is described, which provides an environmentally benign, efficient, and practical route for the generation of 2-aminobenzothiazole. This present tandem process shows broad substrate scope in the presence of octadecyltrimethylammonium chloride as a phase-transfer catalyst. In addition, the reaction media can be recovered and recycled without loss of efficiency.

Iron-catalyzed tandem reactions of 2-halobenzenamines with isothiocyanates leading to 2-aminobenzothiazoles

Qiu, Jing-Wen,Zhang, Xing-Guo,Tang, Ri-Yuan,Zhong, Ping,Li, Jin-Heng

supporting information; scheme or table, p. 2319 - 2323 (2009/12/29)

A highly practical method for the synthesis of 2-aminobenzothiazoles has been developed through an iron-catalyzed tandem reaction. The present tandem process allows the assembly of a wide range of 2-aminobenzothiazoles by the reactions of 2-halobenzenamin

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