348081-63-0Relevant academic research and scientific papers
New preparation of benzylic zinc reagents via a fragmentation reaction
Piazza, Claudia,Millot, Nicolas,Knochel, Paul
, p. 88 - 95 (2007/10/03)
The fragmentation of sterically hindered homobenzylic zinc alcoholates proceeds readily leading to benzylic zinc reagents free from any Wurtz-coupling product. Reaction of these organometallic intermediates with various aldehydes produces new homobenzylic
Synthesis of carbonyl and dicarbonyl compounds from organometallic reagents and N-imidazolium-N-methyl amides and bis-amides
De Las Heras, Maria A.,Vaquero, Juan J.,Garcia Navio, Jose L.,Alvarez-Builla, Julio
, p. 14297 - 14310 (2007/10/03)
A new method for the synthesis of selective acylating agents is described from the reaction of carboxylic acids with 3-methyl-1-methylamino-3H-imidazol-1-ium salts in the presence of appropriate coupling reagents. The amides and bis-amides thus prepared reacted selectively with organometallics to afford ketones and diketones and with DIBALH to give aldehydes and dialdehydes in high yields.
