34811-27-3

Upstream product

• 856084-55-4 2-(3,4-dimethoxy-phenyl)-propane-1,1,3-tricarboxylic acid triethyl ester 
• 64139-22-6 diethyl 2,4-diacetyl-3-(3,4-dimethoxyphenyl)pentanedionate 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 20583-78-2 3,4-dimethoxy-cinnamic acid ethyl ester 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 36286-18-7 (5,6-dimethoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid 
• 62956-65-4 5,6-dimethoxyindan-1-acetic acid 

Relevant academic research and scientific papers

Synthesis, thermal, rheological characteristics, and enzymatic degradation of aliphatic polyesters with lignin-based aromatic pendant groups

This research aims to produce lignin-based biodegradable polyesters with improved thermal quality. A series of aliphatic polyesters with lignin-based aromatic side groups were synthesized by conventional melt-polycondensation. Decent molecular weight (21–

Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity

A variety of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid were synthesized and screened for their analgesic and anti-inflammatory activities. The compounds were found to have longer activity profile exceeding that of indomethacin in carrageenan-induced rat paw edema model. Few selected compounds were also screened for their antipyretic, anti-arthritic and ulcerogenecity potential. From these studies it can be concluded that these compounds though have significant antipyretic activity did not act through the inhibition of TNF-α. The test compounds failed to prevent the development of secondary inflammation in adjuvant-induced arthritis assay. However, these compounds showed no ulcer formation at the tested dose level of 100 mg/kg p.o.

Aromatic amide derivatives of 5,6-dimethoxy-2,3-dihydro-1H-inden(-1-yl)acetic acid as anti-inflammatory agents free of ulcerogenic liability

Amide derivatives of 5,6-dimethoxy-2,3-dihydro-1H-inden(-1-yl)acetic acid were synthesized and evaluated for their anti-inflammatory and analgesic activity. Few selected compounds were also screened for their antipyretic, anti-arthritic, and ulcerogenic potential. Most of the compounds exhibited good activity profile and were free of gastrointestinal toxicity of common NSAIDs. However these compounds failed to decrease secondary lesions of adjuvant induced arthritis and also did not inhibit TNF-α in lipopolysaccharide induced pyresis.