34817-21-5Relevant academic research and scientific papers
A new route for generation of α-λ3-iodanyl ketones via ester exchange of (Z)-(β-acetoxyvinyl)-λ3-iodanes: Their nucleophilic substitutions with halides and sulfur and phosphorus nucleophiles
Ochiai, Masahito,Nishitani, Junichi,Nishi, Yoshio
, p. 4407 - 4413 (2002)
An efficient method for generation of α-λ3-iodanyl ketones from (Z)-(2-acetoxyvinyl)(phenyl)-λ3-iodanes was developed. The method involves ester exchange of (Z)-2-acetoxyvinyl-λ3-iodanes with methanol in the presence of triethylamine. α-λ3Iodanyl ketones react with a variety of nucleophiles such as halides, thiols, phosphines, phosphinic acids, and phosphates, under the conditions which produce α-functionalized carbonyl compounds probably via an SN2 pathway.
