34843-88-4 Usage
Uses
Used in Pharmaceutical Industry:
[(2,5-Dimethyl-3-thienyl)methyl]amine hydrochloride is used as a precursor in the synthesis of complex organic molecules for the development of new pharmaceuticals. Its unique chemical structure allows for the creation of a wide range of compounds with potential therapeutic applications.
Used in Research Applications:
In the field of research, [(2,5-Dimethyl-3-thienyl)methyl]amine hydrochloride serves as an essential tool for studying various chemical reactions and understanding the behavior of amine compounds. Its properties make it a valuable asset in the development of new methodologies and techniques in chemical research.
Used in Agrochemical Production:
[(2,5-Dimethyl-3-thienyl)methyl]amine hydrochloride is also utilized in the production of agrochemicals, where its chemical properties contribute to the development of effective and targeted products for agricultural use. Its role as a precursor in the synthesis of complex organic molecules enables the creation of compounds with specific pesticidal or herbicidal properties.
Check Digit Verification of cas no
The CAS Registry Mumber 34843-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,8,4 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 34843-88:
(7*3)+(6*4)+(5*8)+(4*4)+(3*3)+(2*8)+(1*8)=134
134 % 10 = 4
So 34843-88-4 is a valid CAS Registry Number.
34843-88-4Relevant academic research and scientific papers
Design and synthesis of heteroaromatic-based benzenesulfonamide derivatives as potent inhibitors of H5N1 influenza A virus
Yu, Yongshi,Tazeem,Xu, Zhichao,Du, Liaoqi,Jin, Mengyu,Dong, Chune,Zhou, Hai-Bing,Wu, Shuwen
, p. 89 - 100 (2019/01/30)
Influenza A virus is an enveloped negative single-stranded RNA virus that causes febrile respiratory infection and represents a clinically challenging threat to human health and even lives worldwide. Even more alarming is the emergence of highly pathogenic avian influenza (HPAI) strains such as H5N1, which possess much higher mortality rate (60%) than seasonal influenza strains in human infection. In this study, a novel series of heteroaromatic-based benzenesulfonamide derivatives were identified as M2 proton channel inhibitors. A systematic investigation of the structure-activity relationships and a molecular docking study demonstrated that the sulfonamide moiety and 2,5-dimethyl-substituted thiophene as the core structure played significant roles in the anti-influenza activity. Among the derivatives, compound 11k exhibited excellent antiviral activity against H5N1 virus with an EC50 value of 0.47 μM and selectivity index of 119.9, which are comparable to those of the reference drug amantadine.
