348584-45-2Relevant academic research and scientific papers
1,2-epimino-3,4-epoxybutane: A versatile chiral building block
Harms,Schaumann,Adiwidjaja
, p. 577 - 580 (2007/10/03)
The synthesis of enantiomerically pure 1,2-epimino-3,4-epoxy-(N-toluenesulfonyl)butane (6) in the S,R-(erythro) and R,R-(threo) configurations is described. This building block offers a new route to targets with an 1,2-aminohydroxy functionality. As an example, the new 1,4-biselectrophile is employed in a cyclopentane synthesis.
