348640-88-0

Basic information

• Product Name: Benzonitrile, 3-bromo-4-(dimethylamino)-
• CAS NO: 348640-88-0
• Molecular Formula: C9H9BrN2
• Molecular Weight: 225.088
• Mol File: 348640-88-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 3-bromo-4-(dimethylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-bromo-4-(dimethylamino)-(348640-88-0)
• EPA Substance Registry System: Benzonitrile, 3-bromo-4-(dimethylamino)-(348640-88-0)

Safety Data

• Hazardous Substances Data: 348640-88-0(Hazardous Substances Data)

Upstream product

• 2206-27-1 dimethylsulfoxide-d6 
• 535-11-5 Ethyl 2-bromopropionate 
• 1197-19-9 4-cyano-N,N-dimethylaniline 
• 128-08-5 N-Bromosuccinimide 
• 62820-00-2 4-cyano-N,N-dimethylaniline-N-oxide 
• 1428637-16-4 C₁₀H₁₃BrN₂O 
• 108-24-7 acetic anhydride 

Downstream Products

• 220844-83-7 3-bromo-4-(dimethylamino)benzoic acid 

Relevant articles and documents

Catalyst and Additive-Free Direct Amidation/Halogenation of Tertiary Arylamines with N-haloimide/amides

An approach has been developed for the amidation (halogenation) of tertiary arylamines by electrophilic activation using N-haloimide/amides. Several control experiments have been performed, and the coupling reaction outcomes indicated that the N-haloimide/amide brings three major functions, including electrophilic activation, aromatic halogenation and nucleophilic nitrogen sources. This cascade reaction features simple manipulation, requires no additional catalyst, oxidant or additives, and is performed under mild conditions. (Figure presented.).

Ruthenium-catalyzed intramolecular selective halogenation of O-methylbenzohydroximoyl halides: A new route to halogenated aromatic nitriles

The intramolecular halogenation of O-methylbenzohydroximoyl halides in the presence of a Ru catalyst and the ligand diphenylacetylene afforded halo substituted aromatic nitriles in a highly regioselective manner. Further, substituted nitriles were converted into substituted tetrazole derivatives in the presence of NaN3 and I2.

2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF

The present invention discloses fused bicyclic 2-aryl- or 2-heteroarylthiazolyl compounds and their pharmaceutically acceptable salts and esters thereof, which are useful for inhibiting the growth of cancerous cells, inhibiting human breast carcinoma tumo