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Ethanone, 2-diazo-1-[4-(1,1-dimethylethyl)phenyl]-, also known as 2-diazo-1-[4-(tert-butyl)phenyl]ethanone, is a chemical compound with the molecular formula C11H14N2O. It is a colorless to pale yellow crystalline solid that is sensitive to light and heat. Ethanone, 2-diazo-1-[4-(1,1-dimethylethyl)phenyl]- is an important intermediate in the synthesis of various organic compounds, particularly in the preparation of pharmaceuticals and agrochemicals. It is used in the formation of heterocyclic compounds and as a reagent in the diazotization reaction. Due to its reactivity, it is essential to handle Ethanone, 2-diazo-1-[4-(1,1-dimethylethyl)phenyl]- with care, following proper safety protocols to minimize the risk of explosion or other hazardous reactions.

3488-46-8

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3488-46-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3488-46-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,8 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3488-46:
(6*3)+(5*4)+(4*8)+(3*8)+(2*4)+(1*6)=108
108 % 10 = 8
So 3488-46-8 is a valid CAS Registry Number.

3488-46-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-tert-butyl-phenyl)-2-diazo-ethanone

1.2 Other means of identification

Product number -
Other names 2-[4-tert.-Butyl-phenyl]-2-oxo-diazoethan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3488-46-8 SDS

3488-46-8Relevant academic research and scientific papers

Tandem Synthesis of α-Diazoketones from 1,3-Diketones

Zhang, Jianlan,Chen, Wenwen,Huang, Dayun,Zeng, Xiaobao,Wang, Xinyan,Hu, Yuefei

, p. 9171 - 9174 (2017/09/11)

A highly efficient synthesis of α-diazoketone was achieved by simply stirring the mixture of 1,3-diketone, TsN3, and MeNH2 in EtOH. It was a tandem reaction including a novel primary amine-catalyzed Regitz diazo transfer of 1,3-diket

Quinolones as gonadotropin releasing hormone (GnRH) antagonists: Simultaneous optimization of the C(3)-aryl and C(6)-substituents

Young, Jonathan R.,Huang, Song X.,Chen, Irene,Walsh, Thomas F.,DeVita, Robert J.,Wyvratt Jr., Matthew J.,Goulet, Mark T.,Ren, Ning,Lo, Jane,Yang, Yi Tien,Yudkovitz, Joel B.,Cheng, Kang,Smith, Roy G.

, p. 1723 - 1727 (2007/10/03)

A series of 3-arylquinolones was prepared and evaluated for their ability to act as gonadotropin releasing hormone (GnRH) antagonists. A variety of substitution patterns of the 3-aryl substituent are described. The 3,4,5-trimethylphenyl substituent (23h) was found to be optimal. (C) 2000 Elsevier Science Ltd. All rights reserved.

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