929643-04-9Relevant academic research and scientific papers
1-Methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalene derivatives as non-steroidal progesterone receptor antagonists
Kern, Jeffrey C.,Terefenko, Eugene,Trybulski, Eugene,Berrodin, Thomas J.,Cohen, Jeffrey,Winneker, Richard C.,Yudt, Matthew R.,Zhang, Zhiming,Zhu, Yuan,Zhang, Puwen
scheme or table, p. 4816 - 4818 (2010/10/02)
Non-steroidal 1-methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalenes and acyclic derivatives were evaluated as novel series of progesterone receptor (PR) antagonists using the T47D cell alkaline phosphatase assay. Moderate to potent PR antag
5-Aryl-indan-1-ol and analogs useful as progesterone receptor modulators
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Page/Page column 15, (2010/11/26)
Compounds of formula I are provided, wherein R1-R9 and n are defined herein, and pharmaceutical compositions and kits containing these compounds. Also provided are methods of inducing contraception, providing hormone replacement ther
5-Aryl-indan-1-one and analogs useful as progesterone receptor modulators
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Page/Page column 16, (2010/11/26)
Compounds of formula I or II are provided, wherein R1—R8 are defined herein, and pharmaceutical compositions and kits containing these compounds. Also provides are methods of inducing contraception, providing hormone replacement ther
