3489-63-2

Upstream product

• 89722-87-2 7-chloro-2-methylamino-5-phenyl-3-trifluoroacetoxy-3H-1,4-benzodiazepine 
• 58-25-3 chlordiazepoxide 

Downstream Products

• 62167-20-8 7-chloro-4-ethoxyoxalyl-9-phenyl-4H-benzo[e]oxazolo[5,4-b][1,4]diazepine-2-carboxylic acid ethyl ester 
• 62167-22-0 7-Chlor-3a,10a-dihydro-3-methyl-9-phenyl-oxazolo<4,5-b><1,4>benzodiazepin-2(3H)-on 
• 76458-57-6 7-Chloro-2-methylamino-5-phenyl-3-piperidinyl-3H-1,4-benzodiazepine 
• 76458-52-1 7-Chloro-3-dimethylamino-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 
• 76458-58-7 7-Chloro-2-methylamino-3-morpholino-5-phenyl-3H-1,4-benzodiazepine 
• 76458-56-5 7-Chloro-2-methylamino-5-phenyl-3-pyrrolidinyl-3H-1,4-benzodiazepine 
• 76458-53-2 7-Chloro-3-diethylamino-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 
• 76458-54-3 3-Benzylmethylamino-7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 
• 76458-55-4 7-Chloro-2-methylamino-3-methylphenylamino-5-phenyl-3H-1,4-benzodiazepine 

Relevant academic research and scientific papers

3-FLUOROBENZODIAZEPINES

Benzodiazepines that bear a fluorine substituent in the metabolically active C-3 position were prepared by the reaction of diethylaminosulfur trifluoride (DAST) with the corresponding 3-hydroxybenzodiazepines.These products are surprisingly stable to hydrolysis and possess potent antianxiety and muscle-relaxing properties.