3490-49-1

Basic information

• Product Name: 2-phenoxycyclohexa-2,5-diene-1,4-dione
• CAS NO: 3490-49-1
• Molecular Formula: C₁₂H₈O₃
• Molecular Weight: 200.1901
• Mol File: 3490-49-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 313.3°C at 760 mmHg
• Flash Point: 137.9°C
• Density: 1.304g/cm³
• Vapor Pressure: 0.000502mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 2-phenoxycyclohexa-2,5-diene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenoxycyclohexa-2,5-diene-1,4-dione(3490-49-1)
• EPA Substance Registry System: 2-phenoxycyclohexa-2,5-diene-1,4-dione(3490-49-1)

Safety Data

• Hazardous Substances Data: 3490-49-1(Hazardous Substances Data)

Usage

General Description

2-phenoxycyclohexa-2,5-diene-1,4-dione is a chemical compound with the molecular formula C12H8O3. It is a derivative of cyclohexane and is also known as 4-Hydroxy-6-oxo-1,3-cyclohexadienyliden-1-yl benzene. 2-phenoxycyclohexa-2,5-diene-1,4-dione is a yellow crystalline solid that is used in the production of dyes and pigments. It is also used in organic synthesis as a starting material for the production of various other compounds. 2-phenoxycyclohexa-2,5-diene-1,4-dione is classified as a cyclic ketone and contains a benzene ring attached to a cyclohexadienone moiety, making it useful in a variety of chemical reactions and applications.

Upstream product

• 106-51-4 p-benzoquinone 
• 3958-83-6 2-iodocyclohexa-2,5-diene-1,4-dione 
• 108-95-2 phenol 
• 2417-10-9 o-Phenoxyphenol 
• 20244-55-7 2,4,4,6-tetrachlorocyclohexa-2,5-dien-1-one 
• 13331-18-5 2-phenoxy-1,4-dihydroquinone 
• 3958-82-5 2-bromo-1,4-benzoquinone 
• 744196-30-3 4-Amino-2-phenoxy-phenol 
• 25108-09-2 2,4,6,6-tetrachloro-2,4-cyclohexadienone 
• 1695-04-1 2-methoxyphenyl phenyl ether 
• 467238-62-6 2-(2',4',6'-trichlorophenoxy)-4,4-dimethoxy-6-chlorocyclohexadien-2,5-one 
• 88-06-2 2,4,6-Trichlorophenol 
• 3784-03-0 sodium 2,4,6-trichlorophenolate 
• 467238-65-9 2-(2',4',6'-trichlorophenoxy)-6-chloro-1,4-dihydroquinone 

Downstream Products

• 13331-18-5 2-phenoxy-1,4-dihydroquinone 
• 526-62-5 2,5-bis(1-aziridinyl)-1,4-benzoquinone 

Relevant articles and documents

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation

Under Rh-catalyzed conditions, typically electrophilic 1,4-benzoquinones exhibit nucleophilic reactivity, such that exposure to appropriate electrophiles generates products of C-H iodination, bromination, and phenylselenation. This provides a mild and general method for direct halofunctionalization, and the first method that can achieve direct C-H phenylselenation of this compound class. The scope and limitations of the new protocols are outlined, and representative derivatizations are highlighted.

A New Route to Isodityrosine-derived Cyclic Peptides: Application to K-13

A versatile approach suitable for isodityrosine-derived cyclic peptides, and its application to K-13 have been described.