349098-69-7

Basic information

• Product Name: N-(4-methylpentyl)-4-methylbenzenesulfonamide
• Synonyms: N-(4-methylpentyl)-4-methylbenzenesulfonamide
• CAS NO: 349098-69-7
• Molecular Weight: 255.381
• Mol File: 349098-69-7.mol

Chemical Properties

• CAS DataBase Reference: N-(4-methylpentyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methylpentyl)-4-methylbenzenesulfonamide(349098-69-7)
• EPA Substance Registry System: N-(4-methylpentyl)-4-methylbenzenesulfonamide(349098-69-7)

Safety Data

• Hazardous Substances Data: 349098-69-7(Hazardous Substances Data)

Upstream product

• 626-89-1 4-Methyl-1-pentanol 
• 70-55-3 toluene-4-sulfonamide 
• 5344-20-7 4-methyl pentanamine 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Photoinduced site-selective C(sp3)-H chlorination of aliphatic amides

Herein, we report a new photochemical method for C(sp3)-H chlorination of amides which employs tert-butyl hypochlorite as the chlorinating agent and a household compact fluorescent lamp as the light source. The reaction proceeds via N-heterocyclic carbene SIPr·HCl-promoted N-H chlorination and subsequent photoinduced Hofmann-L?ffler-Freytag chlorine atom transfer. The latter process is facilitated by (diacetoxyiodo)benzene. This protocol exhibits a broad scope and is suitable for site-selective chlorination of methyl hydrogen as well as methylene and methine hydrogen.

Copper-Catalyzed Amide Radical-Directed Cyanation of Unactivated Csp3-H Bonds

A method for site-selective intermolecular δ/?-Csp3-H cyanation of aliphatic sulfonamides is developed using TsCN as the cyanating reagent, catalyzed by a Cu(I)/phenanthroline complex. The mild, expeditious, and modular protocol allows efficient remote Csp3-H cyanation with good functional group tolerance and high regioselectivity. Mechanistic studies indicate that the reaction might proceed through a Cu(I)-mediated N-F bond cleavage to generate an amidyl radical, 1,5-HAT, and cyano group transfer of the resulting carbon radical with TsCN.

Simple and versatile catalytic system for N-alkylation of sulfonamides with various alcohols

"Chemical Equation Presented" A simple and versatile catalytic system for N-alkylation of sulfonamides with various alcohols based on a catalytic hydrogen transfer reaction has been developed under a low catalyst loading of [Cp*lrCl2]2 (0.050-1.5 mol %) in the presence of t-BuOK. A variety of N-alkylated sulfonamides were prepared In good to excellent yields. Mechanistic investigations revealed that the key catalytic species in the present system is a sulfonylimido-bridged unsaturated diirldium complex [(Cp*lr)2(μ-NTs)2].