349103-24-8

Basic information

• Product Name: (11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine
• Synonyms: (11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine;(11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2] dioxaphosphepin-4-amine,99%e.e.
• CAS NO: 349103-24-8
• Molecular Formula: C24H22NO2P
• Molecular Weight: 387.410741
• Product Categories: SF160005
• Mol File: 349103-24-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 566.4±33.0 °C(Predicted)
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.71±0.20(Predicted)
• CAS DataBase Reference: (11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine(349103-24-8)
• EPA Substance Registry System: (11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine(349103-24-8)

Safety Data

• Hazardous Substances Data: 349103-24-8(Hazardous Substances Data)

Usage

General Description

"(11bR)-N,N-Diethyl-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine" is a chemical compound with a complex and unique structure, featuring a phosphorus atom bound to a dioxaphosphepin ring and two naphthalene groups. It is a chiral molecule, with a stereocenter at the 11b position. The compound contains diethylamine and amine functional groups, and its structure suggests potential applications in organic synthesis and medicinal chemistry. The compound's specific properties and potential uses would need to be further studied and characterized through experimentation and analysis.

Upstream product

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Relevant articles and documents

Synthesis and application in asymmetric C-C bond formation of solution phase ligand libraries of monodentate phosphoramidites

The synthesis of solution phase libraries of chiral monodentate phosphoramidite by using the automated parallel protocol was analyzed. It was observed that the method leads to the analysis of effective enantioselective catalysts for tranformations and association with the monodentate ligand combination approach. The automated parallel protocol provided a powerful tool for the combinatorial asymmetric catalysis. The chromatography was performed at the end of the phosphoramidite synthesis by a filtration process, due to more simple automated procedure.

Rapid identification of a scalable catalyst for the asymmetric hydrogenation of a sterically demanding aryl enamide

High throughput screening was used to find a cost-effective and scalable catalyst for the asymmetric hydrogenation of a sterically demanding enamide as an intermediate towards a new potent melanocortin receptor agonist useful in the treatment of obesity.

Catalytic asymmetric alkynylation and arylation of aldehydes by an H 8-binaphthyl-based amino alcohol ligand

A novel chiral H8-1,1'-binaphthyl-based amino alcohol ligand (1Ra,2S,3R)-2 has been synthesized and applied in the direct nucleophilic addition of organozincs (alkynylzinc and arylzinc prepared in situ) to aldehydes, yielding the corresponding optically active propargylic alcohols and diarylmethanols in high yields and good to excellent enantioselectivities. For the asymmetric arylation reaction, one catalyst (1Ra,2S,3R)-2 can afford both enantiomers of many pharmaceutically interesting diarylmethanols by a proper combination of various arylzinc reagents and aldehydes.