34912-38-4Relevant academic research and scientific papers
Process for preparing ketazine by molecular oxygen oxidation method
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Paragraph 0056-0057, (2019/07/04)
The invention discloses a process for preparing ketazine by a molecular oxygen oxidation method, which comprises the following steps: ketimine is prepared, and ketone and ammonia are put into a pressure kettle according to a ratio;a pressure range is adjusted to be1.0-5.0MPa, a temperature range to be30-180 DEG C, and a reaction time to be 3-5 hours to generate the ketimine; the molar ratio of theammonia to the ketone is 1:1-20:1; the temperature and the pressure are reduced, and a mixture of the ketimine and the ketone is separated; the mixture of the ketimine and the ketone, a catalyst anda drying agent are put into a reaction kettle and heated to 30-80 DEG C, molecular oxygen is introduced to perform oxidation reaction, wherein the pressure range is 0-1.0MPa, and the reaction time is3-6 hours, and molecular oxygen included: oxygen or air; ketazine is separated and purified.The method is not only suitable for benzophenone, but also achieves theketazine of aliphatic ketone with fewcarbon atoms. The method has wide source of raw materials, low cost and easy recovery, no saline wastewater, low energy consumption and cost, and is environmentally friendly.
Ruthenium(ii)-catalysed direct synthesis of ketazines using secondary alcohols
Kishore, Jugal,Thiyagarajan, Subramanian,Gunanathan, Chidambaram
supporting information, p. 4542 - 4545 (2019/04/26)
Direct one-pot synthesis of ketazines from secondary alcohols and hydrazine hydrate catalyzed by a ruthenium pincer complex is reported, which proceeds through O-H bond activation of secondary alcohols via amine-amide metal-ligand cooperation in the catalyst. Remarkably, liberated molecular hydrogen and water are the only byproducts.
