3622-62-6

Usage

Uses

Used in Pharmaceutical Industry:
2-(pentan-2-ylidene)hydrazinecarboxamide is utilized as a precursor in the synthesis of new drugs due to its ability to contribute to the development of biologically active molecules. Its unique structure allows it to be a key component in the creation of pharmaceuticals with potential therapeutic applications.
Used in Research and Development:
In the realm of research and development, 2-(pentan-2-ylidene)hydrazinecarboxamide serves as a reagent in organic synthesis and medicinal chemistry. Its properties make it a valuable tool for scientists and researchers working on the discovery and improvement of pharmaceutical compounds.
Used in Organic Synthesis:
2-(pentan-2-ylidene)hydrazinecarboxamide is employed as a building block in organic synthesis, where its hydrazide functional group can be manipulated to form a variety of complex organic molecules with diverse applications.
Used in Medicinal Chemistry:
As a component in medicinal chemistry, 2-(pentan-2-ylidene)hydrazinecarboxamide is used to explore and develop new chemical entities with potential therapeutic effects. Its structural attributes make it a candidate for the design of novel drugs targeting specific biological pathways or diseases.

Upstream product

• 107-87-9 2-Pentanone 
• 563-41-7 semicarbazide hydrochloride 
• 4426-72-6 hydrazine carboxamide 

Downstream Products

• 110-21-4 hydrazodicarboxamide 
• 3741-83-1 pentan-2-one-phenylhydrazone 
• 107-87-9 2-Pentanone 
• 112175-51-6 3-Methyl-2-oxo-3-propyl-2,3-dihydro-indole-1-carboxylic acid phenylamide 
• 34912-38-4 1,2-di(pentan-2-ylidene)hydrazine 

Relevant academic research and scientific papers

Investigating the synergism of some hydrazinecarboxamides and iodide ions as corrosion inhibitor formulations for mild steel in hydrochloric Acid: Experimental and computational studies

Three hydrazinecarboxamides, namely, 2-cyclohexylidenehydrazinecarboxamide (SCYHEX), 2-(pentan-3-ylidene)hydrazinecarboxamide (SP3ONE) and 2-(pentan-2-ylidene)hydrazinecarboxamide (SP2ONE) were tested as inhibitors of acid corrosion of mild steel both without and with addition of iodide ions. The formulated inhibitor solutions showed excellent corrosion inhibition efficiency as they suppressed steel to the tune of 82% without KI additive, and up to 97% with KI additive. The shifts in corrosion potentials recorded from polarization measurements were anodic and ranged from 25 mV to 55 mV (without KI) relative to the uninhibited electrolyte, suggesting that the Schiff bases are mixed-type corrosion inhibitors with prominent effects on anodic dissolution of steel. The inhibitors adsorb at steel/electrolyte interface as reveled by the AC impedance measurements that showed more than 5 times increase in the charge transfer resistance and equivalence decrease in double layer capacitance of the inhibitor-containing solutions compared to the blank. Theoretical density functional theory (DFT) calculations suggested possible covalent interactions between the Schiff bases molecules and Fe with Fe—N and Fe—C bond lengths ranging from 1.87 ? to 1.96 ?. Experimentally derived synergistic parameters for Schiff bases-iodide ions interactions were generally greater than 1 and a strong H—I bond of ca. 2.3 ? length was observed in what appeared to be first time theoretical modelling of inhibitor-iodide ion synergistic interactions. DFT derived reactivity indices of protonated Schiff bases molecules correlated with the observed strengths of corrosion inhibition. Monte Carlo simulations study also confirmed the tendency of the inhibitor molecules to adsorb on mild steel surface and displace corrosive ions from the steel surface.

Reactions of diazoalkanes with isocyanates. Synthesis of imidazolidine-2,4-diones, oxindoles, and oxazolidinones

Thermolysis of a 5,5-dialkyl-Δ3-1,3,4-oxadiazolin-2-one in nitrobenzene containing an aryl isocyanate at 150 deg C affords a 1,3-diaryl-5,5-dialkyl imidazolidine-2,4-dione, an N-arylcarbamoyl-3,3-dialkyloxindole, and a 3-aryl-2-arylimino-5,5-dialkyl-1,3-oxazolidin-4-one.Those products arise from attack of a diazoalkane, generated in situ from the oxadiazolinone by thermal cycloreversion, on the isocyanate function.Two imidazolidine diones, three oxazolidinones, and 14 oxindoles were prepared.