349150-36-3Relevant academic research and scientific papers
Synthesis of phthalan derivatives via a formal intramolecular 1,3-insertion of rhodium(II) azavinyl carbenes into O[sbnd]Si bond
Deng, Changchang,Duan, Shengguo,Jie, Yuchen,Luo, Huan,Xiang, Qiaoyi,Xu, Ze-Feng
, (2021/08/30)
The first formal intramolecular 1,3-insertion into O[sbnd]Si bond of rhodium(II) azavinyl carbene have been developed, and valuable phthalan derivatives could be synthesized efficiently. In addition, various functional groups could be introduced to the pr
Rapid Access to Oxabicyclo[2.2.2]octane Skeleton through Cu(I)-Catalyzed Generation and Trapping of Vinyl-o-quinodimethanes (Vinyl-o-QDMs)?
Luo, Hejiang,He, Chuan,Jiang, Huanfeng,Zhu, Shifa
, p. 1052 - 1056 (2020/07/04)
A Cu(I)-catalyzed three-component reaction of terminal enynals/enynones, diazo compounds, and alkenes has been developed. With this method, a series of oxabicyclo[2.2.2]octanes were effectively synthesized in high yields under mild reaction conditions. This transformation is proposed to proceed through trapping of the cyclic vinyl-o-quinodimethanes (vinyl-o-QDMs) species, which were generated from terminal enynals/enynones and diazo compounds by alkenes. The obvious advantages of wide substrate scopes, mild reaction conditions, and high seteroselectivity and atom efficiency make this reaction highly appealing for construction of highly rigid [2.2.2]octane skeleton.
Tandem Enyne Metathesis-Diels-Alder Reaction for Construction of Natural Product Frameworks
Rosillo, Marta,Dominguez, Gema,Casarrubios, Luis,Amador, Ulises,Perez-Castells, Javier
, p. 2084 - 2093 (2007/10/03)
Enynes connected through aromatic rings are used as substrates for metathesis reactions. The reactivity of three ruthenium carbene complexes is compared. The resulting 1,3-dienes are suitable precursors of polycyclic structures via a Diels-Alder process.
Diastereoselective Pauson-Khand reactions on aromatic substrates
Blanco-Urgoiti, Jaime,Casarrubios, Luis,Domínguez, Gema,Pérez-Castells, Javier
, p. 3315 - 3317 (2007/10/03)
The synthesis of several natural products' frameworks is carried out by means of a diastereoselective intramolecular Pauson-Khand reaction promoted by molecular sieves. Diastereoselectivity is achieved only if a coordinating group is present at a convenie
