34928-12-6

Basic information

• Product Name: 4,4,6-trimethyl-1-phenyl-1,4-dihydropyrimidine-2(3H)-one
• Synonyms: 4,4,6-trimethyl-1-phenyl-1,4-dihydropyrimidine-2(3H)-one
• CAS NO: 34928-12-6
• Molecular Weight: 216.283
• Mol File: 34928-12-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4,4,6-trimethyl-1-phenyl-1,4-dihydropyrimidine-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,6-trimethyl-1-phenyl-1,4-dihydropyrimidine-2(3H)-one(34928-12-6)
• EPA Substance Registry System: 4,4,6-trimethyl-1-phenyl-1,4-dihydropyrimidine-2(3H)-one(34928-12-6)

Safety Data

• Hazardous Substances Data: 34928-12-6(Hazardous Substances Data)

Upstream product

• 16325-43-2 1-phenyl-4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)thione 
• 917-54-4 methyllithium 
• 21139-18-4 4,6-dimethyl-1-phenyl-2-oxopyrimidine 
• 917-64-6 methyl magnesium iodide 

Downstream Products

• 121649-12-5 2-ethoxy-1,4-dihydro-4,4,6-trimethyl-1-phenylpyrimidine 
• 5392-23-4 3,4-dihydro-4,4,6-trimethylpyrimidine-2(1H)-thione 
• 81730-01-0 3,4,5,6-tetrahydro-4,4,6-trimethyl-1-phenyl-2-(1H)pyrimidinone 
• 107400-22-6 6-hydroxyamino-4,4,6-trimethyl-1-phenyl-1,4,5,6-tetrahydropyrimidine-2(3H)-one 
• 81729-99-9 4-anilino-2-methyl-2-methylaminopentane 
• 41275-32-5 7,7-dimethyl-4-phenyl-3-thioxo-6,7-dihydro-3H,4H-[1,2]dithiolo[4,3-d]pyrimidin-5-one 

Relevant articles and documents

Sulphur Extrusion. Part 4. A Halogen-catalysed Conversion of Thiocarbonyl Compounds into their Corresponding Oxygen Analogues using Alkoxides and Hydroxide

The conversion of thiocarbonyl compounds (thioureas, thioamides, and thiones) into their oxygen analogues has been performed using either (i) potassium t-butoxide with iodine, bromine, or chlorine, (ii) sodium ethoxide with bromine or chlorine, or (iii) sodium hydroxide with bromine or chlorine under phase transfer catalysis.

Reaction of Pyrimidin-2(1H)-ones and -thiones with Organometallic Compounds. Regioselective Preparation of Dihydropyrimidin-2(1H)-ones and -thiones

4,6-Dimethyl-1-phenylpyrimidin-2(1H)-one (1) reacted with methylmagnesium iodide to afford 4,6,6-trimethyl-1-phenyl-3,6-dihydropyrimidin-2(1H)-one (8a) selectively; compound (1) reacted with methyl-lithium to give mainly 4,4,6-trimethyl-1-phenyl-3,4-dihydropyrimidin-2(1H)-one (8b).The reactions of various pyrimidin-2(1H)-ones and -thiones with organometallic compounds, and the influence of bulkiness of alkyl groups upon the product ratio, are also discussed.

AN IODINE-POTASSIUM t-BUTOXIDE CATALYSED CONVERSION OF THIAMIDES AND THIOUREAS TO THEIR OXYGEN ANALOGS

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