5392-23-4Relevant articles and documents
-
Takeshima,T. et al.
, p. 2877 - 2880 (1968)
-
Synthesis, anti-inflammatory and analgesic activities evaluation of some mono, bi and tricyclic pyrimidine derivatives
Sondhi, Sham M.,Singh, Nirupma,Johar, Monika,Kumar, Ashok
, p. 6158 - 6166 (2005)
3-Aminobenzonitrile and 2-amino-4-phenyl thiazole on condensation with 4-isothiocyanato-4-methyl pentane-2-one gave condensed monocyclic pyrimidine derivatives 1 and 2, 3, respectively. Condensation of 3-aminopropyl imidazole with 3-isothiocyantobutanal g
SYNTHESIS, STRUCTURE, AND REACTIVITY OF 1,2,3,6-TETRAHYDROPYRIMIDINE-2-THIONES
Shutalev, A. D.,Komarova, E. N.,Pagaev, M. T.,Ignatova, L. A.
, p. 1077 - 1086 (2007/10/02)
Dehydration of 4-hydroxyhexahydropyrimidine-2-thiones formed 1,2,3,6-tetrahydropyrimidine-2-thiones containing no substituent at the C(4) carbon atom.It is shown that the synthesized compounds, in contrast to their 4-alkyl-substituted analogs, react easily with various nucleophilic reactants (alcohols,butylmercaptan, benzenesulfinic acid, hydrazoic acid, p-toluidine) to from the corresponding 4-functionally substituted hexahydropyrimidine-2-thiones.
REACTION OF 2,3-O-ISOPROPYLIDENERIBOFURANOSYLAMINE TOSYLATE WITH 4-METHYL-4-ISOTHIOCYANATO-2-PENTANONE
Shutalev, A. D.,Ignatova, L. A.,Unkovskii, B. V.
, p. 201 - 203 (2007/10/02)
The condensation of 2,3-O-isopropylideneribofuranosylamine tosylate with 4-methyl-4-isothiocyanato-2-pentanone in the presence of bases was studied.In pyridine the reaction gives a mixture of 3-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-4,6,6-trimethyl-1,2,3,6-tetrahydropyrimidine-2-thione and 3-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-4-methylene-6,6-dimethylhexahydropyrimidine-2-thione.